Novel synthesis of ureas: application of t-butylureas.

Chem Pharm Bull (Tokyo)

Research Foundation Itsuu Laboratory, Tokyo, Japan.

Published: January 2010

Otherwise inaccessible tropolonylureas were prepared by reaction of t-butylurea with appropriate amines, with elimination of t-butylamine. This method is also generally applicable for urea synthesis.

Download full-text PDF

Source
http://dx.doi.org/10.1248/cpb.58.82DOI Listing

Publication Analysis

Top Keywords

novel synthesis
4
synthesis ureas
4
ureas application
4
application t-butylureas
4
t-butylureas inaccessible
4
inaccessible tropolonylureas
4
tropolonylureas prepared
4
prepared reaction
4
reaction t-butylurea
4
t-butylurea appropriate
4

Similar Publications

Fibroblasts, non-hematopoietic cells of mesenchymal origin, are tissue architects which regulate the topography of tissues, dictate tissue resident cell types, and drive fibrotic disease. Fibroblasts regulate the composition of the extracellular matrix (ECM), a 3-dimensional network of macromolecules that comprise the acellular milieu of tissues. Fibroblasts can directly and indirectly regulate immune responses by secreting ECM and ECM-bound molecules to shape tissue structure and influence organ function.

View Article and Find Full Text PDF

Decoding the Molecular Basis of the Specificity of an Anti-sTn Antibody.

JACS Au

January 2025

UCIBIO-Applied Molecular Biosciences Unit, Department of Chemistry, NOVA School of Science and Technology, NOVA University Lisbon, 2829-516 Caparica, Portugal.

The mucin -glycan sialyl Tn antigen (sTn, Neu5Acα2-6GalNAcα1--Ser/Thr) is an antigen associated with different types of cancers, often linked with a higher risk of metastasis and poor prognosis. Despite efforts to develop anti-sTn antibodies with high specificity for diagnostics and immunotherapy, challenges in eliciting high-affinity antibodies for glycan structures have limited their effectiveness, leading to low titers and short protection durations. Experimental structural insights into anti-sTn antibody specificity are lacking, hindering their optimization for cancer cell recognition.

View Article and Find Full Text PDF

Efficient photocatalytic degradation of bisphenol A on 2D-3D spherically hierarchical structure ZnInS.

Front Chem

January 2025

Institute of Materials Research, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, Guangdong, China.

Bisphenol A (BPA) poses a significant environmental threat due to its widespread use as an industrial chemical and its classification as an environmental endocrine disruptor. The urgent need for effective BPA removal has driven research toward innovative solutions. In this study, we present the synthesis and application of a novel 2D-3D spherically hierarchical ZnInS (ZIS) photocatalyst for the photocatalytic degradation of BPA under visible light for the first time.

View Article and Find Full Text PDF

Dental pulp stem cells hold significant prospects for tooth regeneration and repair. However, a comprehensive understanding of the molecular differences between dental pulp stem cells (DPSC, from permanent teeth) and stem cells from human exfoliated deciduous teeth (SHED, from deciduous teeth) remains elusive, which is crucial for optimizing their therapeutic potential. To address this gap, we employed a novel data-independent acquisition (DIA) proteomics approach to compare the protein expression profiles of DPSC and SHED.

View Article and Find Full Text PDF

Green Synthesis of Cellulose Acetate Mixed Matrix Membranes: Structure-Function Characterization.

ACS Sustain Chem Eng

January 2025

Department of Chemical and Biomolecular Engineering, Universidad de Cantabria, Av. Los Castros s/n, 39005 Santander, Spain.

Although membrane technology is widely used in different gas separation applications, membrane manufacturers need to reduce the environmental impact during the membrane fabrication process within the framework of the circular economy by replacing toxic solvents, oil-based polymers, and such by more sustainable alternatives. These include environmentally friendly materials, such as biopolymers, green solvents, and surfactant free porous fillers. This work promotes the use of environmentally sustainable and low toxic alternatives, introducing the novel application of cellulose acetate (CA) as a biopolymer in combination with dimethyl carbonate (DMC) as a greener solvent and different inorganic fillers (Zeolite-A, ETS-10, AM-4 and ZIF-8) prepared without the use of toxic solvents or reactants.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!