The rotavirus vaccine was incorporated into the Australian National Immunisation Program from 1 July 2007. To measure early impact of the vaccine on rotavirus disease and the burden of gastroenteritis in young children, we examined 2 surveillance data sources, rotavirus isolates from selected New South Wales laboratories, and New South Wales Emergency Department (ED) visits assigned a gastroenteritis-related diagnosis. Between 2001 and 2008, weekly time series were prepared for 2 age groups representing children young enough to have been offered vaccination prior to the 2008 seasonal epidemic (< 15 months) and older children (15 months to 5 years). In 2008, the seasonal increase in laboratory confirmed rotavirus infection and gastroenteritis related ED visits declined substantially in both age groups compared with earlier years. These data provide preliminary evidence of the effectiveness of the rotavirus vaccination program in New South Wales. Immunising the most susceptible population group, infants, against rotavirus may limit wider circulation of the virus in older children.
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ACS Nano
January 2025
School of Mechanical and Manufacturing Engineering, University of New South Wales, Sydney, New South Wales 2052, Australia.
Implantable systems with chronic stability, high sensing performance, and extensive spatial-temporal resolution are a growing focus for monitoring and treating several diseases such as epilepsy, Parkinson's disease, chronic pain, and cardiac arrhythmias. These systems demand exceptional bendability, scalable size, durable electrode materials, and well-encapsulated metal interconnects. However, existing chronic implantable bioelectronic systems largely rely on materials prone to corrosion in biofluids, such as silicon nanomembranes or metals.
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January 2025
Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Importance: People with kidney failure have a high risk of death and poor quality of life. Mortality risk prediction models may help them decide which form of treatment they prefer.
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CNS Drugs
January 2025
Cornwall Intellectual Disability Equitable Research (CIDER), University of Plymouth, Truro, England.
There is a synergistic relationship between epilepsy and intellectual disability (ID), and the approach to managing people with these conditions needs to be holistic. Epilepsy is the main co-morbidity associated with ID, and clinical presentation tends to be complex, associated with higher rates of treatment resistance, multi-morbidity and premature mortality. Despite this relationship, there is limited level 1 evidence to inform treatment choice for this vulnerable population.
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Centre for Healthy Brain Ageing (CHeBA), University of New South Wales, Sydney, NSW, Australia.
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View Article and Find Full Text PDFAlzheimers Dement
December 2024
Centre for Healthy Brain Ageing (CHeBA), University of New South Wales, UNSW Sydney, NSW, Australia.
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