Study Design: A population based, epidemiological study.
Objective: To investigate incidence of spinal and spinal cord injuries and their surgical treatment in children and adolescents in Finland.
Summary Of Background Data: Epidemiological data on spinal injuries and their treatment in children is sparse.
Methods: All spinal and spinal cord injuries in children under 18 years of age treated in hospital between 1997 and 2006 in Finland were included. The data on injuries, hospitalizations, and surgical treatment were collected from the National Hospital Discharge Register which includes all in-patient treatment episodes. Fatal spinal injuries were derived from the Official Cause-of-Death Statistics of Finland.
Results: The overall incidence of spinal injuries remained stable during the follow-up period, averaging 66 per 10 of the reference population aged below 18 years. The proportions of cervical, thoracic, and lumbar spine injuries altered with age: 64% of spinal injuries in children below 8 years of age were cervical, while in the older children lumbar (42%) and thoracic spine injuries (33%) were more common than cervical. The incidence of spinal cord injuries averaged 1.9 per 10 children. Thirty percent of the children with spinal injury underwent surgery. The annual incidence of fatal spinal injury averaged 2.4 per 10 children.
Conclusion: Pediatric spinal and spinal cord injuries are rare. In contrast to previous literature, the most commonly affected area is lumbar spine. One-third of the children with spinal injury underwent surgery.
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http://dx.doi.org/10.1097/BRS.0b013e3181c64423 | DOI Listing |
Cureus
December 2024
General Medicine, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to Be University), Pune, IND.
ANZ J Surg
January 2025
Middlemore Hospital, Auckland, New Zealand.
Background: To investigate the incidence, demographic characteristics, etiologies, surgical interventions, hospital stays, and neurologic outcomes associated with watersport-related traumatic spinal cord injuries (TSCI) in New Zealand.
Methods: Retrospective study collected data from New Zealand's two spinal rehabilitation units, the Auckland Spinal Rehabilitation Unit (ASRU) and the Burwood Spinal Unit (BSU). It included adults aged over 16 years, between January 2007 and December 2021 with new TSCI secondary to traumatic watersport activities.
Probiotics Antimicrob Proteins
January 2025
Department of Cell and Molecular Biology and Microbiology, Faculty of Biological Science and Technology, University of Isfahan, Isfahan, Iran.
Heat-killed lactobacilli seem to have protective effects against oxidative stress and neurotoxicity. This study aimed to evaluate the antioxidant properties of specific heat-killed lactobacilli extracts and determine their neuroprotective effects against the neurotoxicity induced by blood plasma from people with multiple sclerosis (MS). The antioxidant activity of the three heat-killed lactobacilli was measured using the DPPH assay.
View Article and Find Full Text PDFJ Neurol
January 2025
Department of Neurology, University Hospital Basel, University of Basel, Basel, Switzerland.
Background: With the approval of disease-modifying treatments for 5q-spinal muscular atrophy (SMA), there is an increasing need for biomarkers for disease course and therapeutic response monitoring. Radially sampled Averaged Magnetization Inversion Recovery Acquisitions (rAMIRA) MR-imaging enables spinal cord (SC) gray matter (GM) delineation and quantification in vivo. This study aims to assess SC GM atrophy in patients with 5q-SMA and its associations with clinical disability.
View Article and Find Full Text PDFExp Brain Res
January 2025
Faculty of Sport, Technology and Health Sciences, St. Mary's University, Twickenham, Middlesex, UK.
The aim of this study was to assess if ischaemic preconditioning (IPC) can reduce pain perception and enhance corticospinal excitability during voluntary contractions. In a randomised, within-subject design, healthy participants took part in three experimental visits after a familiarisation session. Measures of pressure pain threshold (PPT), maximum voluntary isometric force, voluntary activation, resting twitch force, corticospinal excitability and corticospinal inhibition were performed before and ≥10 min after either, unilateral IPC on the right leg (3 × 5 min); a sham protocol (3 × 1 min); or a control (no occlusion).
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