AI Article Synopsis
- Oral cancer varies by subtype and location, with different causes and survival rates; squamous cell carcinoma (SCC) is the most common among older men, while lymphoma and sarcoma are most prevalent in those under 20.
- Data from the Israel National Cancer Registry (1970-2006) reveals that the lips have the highest survival rate, whereas the tongue and gums have the lowest.
- Early detection is key for improved survival, and routine oral examinations should be performed, especially for high-risk individuals and areas.
Article Abstract
Background: Oral cancer is one of the few life-threatening oral diseases. The subtypes and different sites of oral cancer has different etiology epidemiology and survival rate. Prevalence of the various anatomical oral sites provided potential baseline for improvement of clinical approach.
Methods: Incidence and survival rates were derived from the Israel National Cancer Registry and included all registered data between 1970 and 2006. Oral cancer included the lips, tongue, buccal mucosa, gums, vestibulum, floor of the mouth, and palate.
Results: Most prevalent oral cancer subtype was squamous cell carcinoma (SCC) among men above the age of 55 years. Females had a higher incidence of SCC in lateral border of tongue, gums and buccal mucosa. Lymphoma and sarcoma were the most prevalent under the age of 20. Melanomas and metastatic disease revealed the lowest survival rate, while invasive or infiltrating basal cell carcinoma in the lips had the highest rate. The highest oral survival rate was for the lip, and the lowest was for the tongue and gums.
Conclusions: Early detection of oral cancer is important for all the medical health team. Decrease in lip carcinoma may be a result of occupational or awareness changes and should be studied. Non-epithelial tumors under the age of 20 should be considered as a differential diagnosis. A basic oral examination should be included in all routine medical examinations, with emphasis on high-risk patients and high-risk oral sites.
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| http://dx.doi.org/10.1111/j.1600-0714.2009.00845.x | DOI Listing |
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