Introduction: Cocaine use is an uncommon condition in older people, a population in which cocaine use is probably overlooked. Cases initiation of use in late adulthood as well as elderly relapsing to use from youth drug use have been reported.
Clinical Case: We report a woman of 61 years of age hospitalized in the detoxification unit for cocaine dependence tratment (used 1-1,5g/ day). She did not begin cocaine use until she was 60 years old. Some risk factors include retirement, chronic pain, and affective symptoms are related with loneliness and increased cocaine use in elderly, and account for the underreporting of abuse or dependence. Old people have more medical conditions related to cocaine use and have greater health deterioration than young people. DISCUSION: Cocaine use should be evaluated in every patient, and elderly patients should be checked particularly when presenting atypical medical or psychiatric conditions.
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Background: Insulinoma is a neuroendocrine tumor, the main manifestation of which is hypoglycemia. However, the symptoms of hypoglycemia can be non-specific for a long time, especially outside provocative conditions, and quite often the tumor manifests from a life-threatening condition - hypoglycemic coma. In this regard, timely laboratory diagnosis of insulinoma and determination of its aggressive course is one of the priorities in modern researches.
View Article and Find Full Text PDFJAMA Netw Open
January 2025
Department of Psychiatry, Harvard Medical School, Boston, Massachusetts.
Importance: During buprenorphine treatment for opioid use disorder (OUD), risk factors for opioid relapse or treatment dropout include comorbid substance use disorder, anxiety, or residual opioid craving. There is a need for a well-powered trial to evaluate virtually delivered groups, including both mindfulness and evidence-based approaches, to address these comorbidities during buprenorphine treatment.
Objective: To compare the effects of the Mindful Recovery Opioid Use Disorder Care Continuum (M-ROCC) vs active control among adults receiving buprenorphine for OUD.
Acta Odontol Scand
January 2025
Associate Laboratory i4HB-Institute for Health and Bioeconomy, University Institute of Health Sciences-CESPU, Gandra 4585-116, Portugal; UCIBIO-Applied Molecular Biosciences Unit, Translational Toxicology Research Laboratory, University Institute of Health Sciences (1H-TOXRUN, IUCS-CESPU), Gandra, Portugal.
Background: The dependence on the illicit drugs has been proven to be harmful to the oral cavity and may lead to a series of abnormal manifestations. The main objective of this study was to observe the effects caused by the consumption of illicit drugs in the oral cavity, in a prison population in the North of Portugal.
Methods: A cross-sectional observational study was conducted involving 91 male inmates aged 25-75 years (mean age 41.
JMIR Form Res
January 2025
Center on Substance Use and Health, San Francisco Department of Public Health, San Francisco, CA, United States.
Background: Despite increasing fatal stimulant poisoning in the United States, little is understood about the mechanism of death. The psychological autopsy (PA) has long been used to distinguish the manner of death in equivocal cases, including opioid overdose, but has not been used to explicitly explore stimulant mortality.
Objective: We aimed to develop and implement a large PA study to identify antecedents of fatal stimulant poisoning, seeking to maximize data gathering and ethical interactions during the collateral interviews.
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