Objective: Recently, epicardial ablation on a beating heart has been conducted as a minimally invasive surgical procedure for atrial fibrillation. We have developed a suction support adapter with the aim of ensuring contact between the ablation probe and the atrial wall to obtain transmural coagulation, and we evaluated the effectiveness of the adapter in electrophysiologic and histopathologic procedures.
Methods: To ensure contact between the radiofrequency ablation probe and the atrial wall, we designed and fabricated a suction support adapter. Twelve pigs were used in this study. A comparison was made between a group in which the ablation probe alone was used (group C, n = 6) and a group in which the ablation probe was used with the adapter (group S, n = 6). In both groups, epicardial ablation was conducted on a beating heart. An electrophysiologic evaluation was conducted to determine whether there was electrical isolation. Histopathologic evaluations were performed to identify the range of coagulation in the resected atrial wall specimens.
Results: The coagulation range was significantly deeper in group S than in group C, and the breadth was significantly narrower. Transmural coagulation and electrical isolation of the atrial wall were seen in 1 case in group C and in all cases in group S.
Conclusions: Using the suction support adapter, we were able to maintain good contact between the ablation probe and the atrial wall. This device is thus thought to be useful for the safe and reliable performance of epicardial ablation on a beating heart.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.jtcvs.2009.10.019 | DOI Listing |
Anesthesiology
December 2024
In Residence, Department of Anesthesiology, University of California San Diego, La Jolla, CA, USA.
Background: Traumatic rib fractures are associated with pain lasting weeks to months and a decreased ability to inspire deeply or cough to clear secretions. Ultrasound-guided percutaneous cryoneurolysis involves reversibly ablating peripheral nerve(s) using exceptionally low temperature with a transdermal probe, resulting in a prolonged nerve block with a duration measured in months. We hypothesized that cryoneurolysis would improve analgesia and inspired volume following rib fracture.
View Article and Find Full Text PDFFood Chem
December 2024
Sensors and Biosensors Group, Analytical Chemistry and Electrochemistry Lab (LR99ES15), University of Tunis El Manar, Tunis El Manar, 2092 Tunis, Tunisia. Electronic address:
Improper use and harmful effects of nitrite ions pose a significant risk to human health. To address this concern, the use of carbon-based materials for electrochemical sensing is regarded as one of the most promising detection tools for ensuring the quality of drinking water and food products. In this context, we developed laser-ablated graphene electrodes (LAGEs) by direct laser scribing on a polyimide substrate, which were subsequently modified by electrochemical deposition of a redox-active melanin-like film (MeLF/LAGEs).
View Article and Find Full Text PDFAnal Chem
December 2024
Department of Hepatobiliary Surgery, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410005, Hunan Province China.
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy, but there is limited improvement in its treatment. Near-infrared fluorescence (NIRF) imaging could potentially address the clinical challenges of PDAC. Indocyanine green (ICG) has been widely used in clinical practice; however, its short half-life and lack of active targeting greatly limit its application in pancreatic surgery.
View Article and Find Full Text PDFJ Cardiothorac Surg
December 2024
Department of Cardiovascular Medicine, Deyang People's Hospital, No. 173, Section 1, Taishan North Road, Jingyang District, Deyang, Sichuan Province, 618000, China.
Background: Paroxysmal atrial fibrillation (PAF) usually recurs after radiofrequency ablation (RFA). This study probed the predictive value of monocyte count to high-density lipoprotein cholesterol (HDL-C) ratio (MHR) with left atrial diameter (LAD) for post-RFA recurrence in PFA patients.
Methods: Totally 210 RFA-treated PAF patients were selected and assigned into Recurrence and Non-Recurrence groups, with clinical baseline data recorded.
J Am Coll Radiol
December 2024
Department of Interventional Radiology: The University of Texas MD Anderson Cancer Center, 1400 Pressler St, Pickens Academic Tower, Houston, TX 77030-4000. Electronic address:
Objective: To evaluate the relevance of established surgical risk calculators (SRCs) for predicting complications in patients undergoing percutaneous lung cryoablation (PLC).
Methods: The institution's database was queried for PLC procedures from March 2015 to May 2024, excluding those patients with concomitant local therapies or five or more lesions treated in a single setting. Demographics, frailty metrics as defined by the surgical literature, and procedural variables were collected.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!