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Budd-Chiari syndrome with obstruction in the inferior vena cava causes increased venous pressure in the azygous-hemiazygous system and paravertebral venous plexus, which is transmitted to the epidural venous plexus, devoid of the valves. It causes epidural venous plexus engorgement and venous congestion and may present rarely with low back pain or radiating pain. However, patients developing lower limb weakness as a complication of Budd-Chiari syndrome is an infrequent and severe presentation.

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Article Synopsis
  • Budd-Chiari syndrome (BCS) is a rare, serious condition caused by blocked blood flow from the liver due to clotting.
  • Treatment usually requires long-term blood thinners and methods to unblock the veins.
  • This case report presents a new technique called hepatic venous thromboaspiration, which is used to help reopen the obstructed veins.
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Behçet's Disease (BD) is a multisystem inflammatory disorder that can lead to severe vascular complications, including Budd-Chiari Syndrome (BCS), a rare but life-threatening condition characterized by hepatic vein obstruction. The co-occurrence of BD and inherited thrombophilia, such as Factor V Leiden mutation, significantly increases the risk of thrombosis, complicating the clinical management of affected individuals. In this case, a 16-year-old female initially presented with nonspecific symptoms of generalized fatigue and bone pain, which later progressed to abdominal distension and significant hepatosplenomegaly.

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Direct Oral Anticoagulants in Budd-Chiari Syndrome.

Eur J Haematol

December 2024

Department of Medicine, Division of Hematology/Oncology, University of South Florida, Tampa, Florida, USA.

Aims: Budd-Chiari syndrome (BCS) is managed by interventions aimed at relieving hepatic venous obstruction and anticoagulation. Despite robust data supporting the tolerability and efficacy of direct oral anticoagulants (DOACs) in patients with other venous thromboembolism, its utility in BCS is not well documented. This study aims to evaluate the efficacy and tolerability of DOACs in Primary BCS from the available literature.

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Introduction/background: Budd-Chiari syndrome is a rare entity that is caused by an obstruction of the flow in the hepatic veins or inferior vena cava.

Case Presentation: Herein, we report a rare case of iatrogenic Budd-Chiari syndrome. A 52-year-old woman with chronic renal failure under hemodialysis, presented to our hospital for dyspnea caused by a large pleural effusion.

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