A 47-year-old male presented to our Hospital in February 2005 with acute colonic obstruction due to transverse colon cancer. The patient had undergone emergency transverse colectomy with loop colostomy. After stabilization of patient's general condition, a further investigation revealed multiple liver metastases. The patient had a further multidisciplinary management with surgical lateral hepatectomy 10 weeks after the first presentation. Furthermore, radiofrequency ablation (RFA) used for other liver metastases, and likewise chemotherapy with S-1. This patient also had 7 sessions of RFA within 3 years for different liver metastases. In May 2008, CT abdomen revealed metastases surrounding superior mesenteric artery lymph nodes and more of liver metastases. Chemotherapy started in May 2008 till February 2009 with mFOLFOX6+bevacizumab (a total of 16 sessions). In November 2008, liver metastases vanished and lymph nodes had shrunken. In February 2009, we performed stereotactic radiotherapy on the lymph nodes metastases and one more session of mFOLFOX6, He showed no visible abdominal metastases on CT scan. The patient is currently in good health with no residual symptoms. The loco-regional cancer treatment with chemo, radiotherapy, RFA as well as surgery improved patient's survival with advanced colonic cancer and added to a quality of life.

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