We report a case of rectal cancer with distant metastases, which was successfully treated with multidisciplinary treatments. The 60s female underwent an abdomino-perineal resection (APR) for low rectal cancer. One year after the APR, two hepatic metastases were found and initially treated by radiofrequency ablation and later by hepatectomy. One month after the hepatectomy, three pulmonary metastases of 10 mm in diameter were found in the right lung. Several regimens of chemotherapy (S-1, CPT-11 and FOLFOX6) were performed. After 3 years of chemotherapy, pulmonary metastases re- grew in size but no new lesion developed. Pneumonectomy was performed to remove all metastatic tumors. A half year after the initial pneumonectomy, a new metastasis was found in the left lung, which was again removed by surgery after 6 months of observation. Postoperative course was uneventful, and she is alive without recurrence for 7 years since the initial rectal surgery.
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Abdom Radiol (NY)
January 2025
Department of Radiology, Taizhou Municipal Hospital, Taizhou, Zhejiang, China.
Background: To develop and validate a clinical-radiomics model for preoperative prediction of lymphovascular invasion (LVI) in rectal cancer.
Methods: This retrospective study included data from 239 patients with pathologically confirmed rectal adenocarcinoma from two centers, all of whom underwent MRI examinations. Cases from the first center (n = 189) were randomly divided into a training set and an internal validation set at a 7:3 ratio, while cases from the second center (n = 50) constituted the external validation set.
Surg Today
January 2025
Department of Surgery, Yokohama City University Hospital, 3-9, Fukuura, Kanazawa-Ku, Yokohama, Kanagawa, 236-0004, Japan.
Purpose: In recent years, major advancements have been made in rectal cancer surgery with the introduction of new techniques such as robotic surgery and indocyanine green fluorescence imaging (ICG-FI). This study aimed to evaluate the comprehensive risk factors for anastomotic leakage (AL) following rectal cancer surgery, incorporating recently introduced techniques and other existing factors, to reflect current practices.
Methods: A retrospective analysis was conducted of 304 patients who underwent either robotic or laparoscopic anterior resection between January 2019 and December 2023.
Integr Cancer Ther
January 2025
University of Las Palmas de Gran Canaria (ULPGC), Las Palmas de Gran Canaria, Spain.
Background: Numbness and tingling secondary to chemotherapy-induced peripheral neuropathy (CIPN) are frequent side effects that limit chemotherapy treatment and quality of life. Successful treatments for CIPN are limited. This preliminary report shows the potential long-term effects of ozone treatment in the management of persistent numbness and tingling secondary to CIPN.
View Article and Find Full Text PDFColorectal Dis
January 2025
Division of General Surgery, Department of Surgery, Queen's University, Kingston, Ontario, Canada.
Aim: Local excision (LE) for T1 rectal cancer may be recommended in those with low-risk disease, while resection is typically recommended in those with a high risk of luminal recurrence or lymph node metastasis. The aim of this work was to compare survival between resection and LE.
Method: This was a population-based retrospective cohort study set in the Canadian province of Ontario.
J Clin Med
December 2024
General Surgery Department, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Colorectal cancer (CRC) is the third most diagnosed cancer worldwide and the second most common cause of cancer death. About 20% of patients diagnosed with rectal cancer present with emergency symptoms. Typical symptoms include acute bleeding, obstruction, and perforation.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!