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Percutaneous chemical myotomy using botulium neurtoxin A under local anaesthesia in the treatment of cricopharyngeal dysphagia following laryngectomy. | LitMetric

AI Article Synopsis

  • The study aimed to evaluate the effectiveness of botulinum neurotoxin A injections for treating swallowing difficulties in patients who had undergone laryngectomy.
  • Fifteen patients participated, receiving the injections under local anesthesia while being monitored using video-fluoroscopy, and their outcomes were assessed over four months.
  • Results showed that 87% of patients experienced improvement in swallowing, indicating that this method is a safe and cost-effective treatment option for post-laryngectomy dysphagia.

Article Abstract

Objective: The purpose of this study was to evaluate the outcome of the use of percutaneous injection of botulinum neurotoxin A under local anaesthesia in the management of cricophayngeus dysphagia in post-laryngectomy patients.

Methods: Fifteen post-laryngectomy patients (6 males, 9 females, age range 48-72 years) with surgery performed not less than five years with post-operative radiotherapy were recruited. Under video-fluoroscopic control and the attachment of a metal safety pin to the neck as a topographical marker for the cricopharyngeus muscle, botulinum neurotoxin was injected after local anaesthesia infiltration. Patients were followed up for a 4 months period with repeated video-fluoroscopy and telephone self-assessment and weight change.

Results: Eighty seven percent of patients noticed some improvement in their dysphagia. One patient reported an adverse reaction of pain at the site of injection.

Conclusion: Percutaneous local injection of botulinum neurotoxin A is a simple, safe and cost-effective means of improving cricopharyngeal dysphagia in post-laryngectomy patients when general anaesthesia is contra-indicated.

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Source
http://dx.doi.org/10.1016/j.anl.2009.11.008DOI Listing

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