Sebaceous adenoma of the salivary gland is a rare tumor comprising 0.1% of all salivary gland neoplasms and less than 0.5% of salivary adenomas. Histologically, sebaceous adenomas are benign neoplasms consisting of sebaceous cells arranged in nests forming acinar and duct-like structures. Oncocytic metaplasia may also occur in some areas. We describe a case of sebaceous adenoma in the submandibular gland. Under a presumptive diagnosis of sialadenitis/sialolithiasis, the patient was administered multiple courses of antibiotics; however, these were not effective. Excisional biopsy resulted in a diagnosis of sebaceous adenoma. A 1-year follow-up showed no recurrence.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2334/josnusd.51.641 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Sebaceous gland hyperplasia is a benign cutaneous entity commonly seen in older men. Occasionally, it can develop in young patients on immunosuppression with cyclosporine or in adolescent boys in the peripubertal age group. It is extremely rare in young children with no reports of eyelid involvement.
View Article and Find Full Text PDFRecurrent GRHL fusions in a subset of sebaceoma: microscopic and molecular characterisation of eight cases.
Histopathology
November 2024
Department of Pathology, Université de Tours, Centre Hospitalier Universitaire de Tours, Tours, France.
Aims: Sebaceous neoplasms constitute a group of adnexal tumours, including sebaceous adenoma, sebaceoma and sebaceous carcinoma. Although mismatch repair deficiency may be observed, the nature of the genetic alterations contributing to the development of most of these tumours is still unknown. In the present study, we describe the clinical, microscopic, and molecular features of eight sebaceomas with GRHL gene rearrangement.
View Article and Find Full Text PDF-Mutated Lynch Syndrome With 9 Synchronous Colon and Rectum Adenocarcinomas: An Extremely Rare Case Report.
Int J Surg Pathol
November 2024
Department of Laboratory Medicine and Pathology, Geisinger Medical Center, Danville, PA, USA.
Synchronous colorectal carcinoma is having more than 1 primary carcinoma detected in a single patient at the same time or within 6 months of tumor diagnosis. Metachronous colorectal carcinoma is the presence of more than 1 primary carcinoma detected consecutively in a single person after a set time interval. Patients with Lynch syndrome and Muir-Torre syndrome (a subset of Lynch syndrome) inherit a germline mutation in 1 of the mismatch repair (MMR) genes.
View Article and Find Full Text PDFSebaceoma of the Eyelid Originating in a Meibomian Gland: A Rare Case and Literature Review.
Cureus
October 2024
Department of General and Clinical Pathology, Forensic Medicine and Deontology, Medical University of Varna, Varna, BGR.
Article Synopsis
- - Sebaceoma is a rare benign tumor with sebaceous gland characteristics, commonly found on the face, scalp, or trunk, and extremely seldom in the eyelid region.
- - Only five cases of eyelid sebaceoma have been documented, with one case linked to a Meibomian gland, emphasizing the rarity of this condition.
- - A recent case is reported involving a 64-year-old male with sebaceoma of the left lower eyelid margin, diagnosed through histopathological examination amidst challenges in distinguishing it from other skin lesions.
Gardner syndrome in a Tunisian family: Identification of a rare APC mutation through targeted NGS.
Gene
January 2025
Center of Biotechnology of Sfax, Laboratory of Eukaryotes Molecular Biotechnology. University of Sfax, Tunisia. Electronic address:
Gardner syndrome (GS) is a subtype of familial adenomatous polyposis (FAP) characterized by colorectal polyps, multiple osteomas, soft tissue tumors, and specific oral manifestations, such as jaw osteomas. GS is caused by mutations in the APC gene, resulting in a nonfunctional protein. This study reports a comprehensive clinical evaluation and genetic analysis of a Tunisian family affected by GS.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!