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Acute encephalopathy associated with influenza A infection in adults. | LitMetric
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Acute encephalopathy associated with influenza A infection in adults.

Nelson Lee Chun Kwok Wong Paul K S Chan Niklas Lindegardh Nicholas J White Frederick G Hayden Edward H C Wong Ka Shing Wong Clive S Cockram Joseph J Y Sung David S C Hui

Emerg Infect Dis

Division of Infectious Diseases, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, 9/F Clinical Sciences Building, Department of Medicine and Therapeutics, Shatin, Hong Kong, People's Republic of China.

Published: January 2010

We report acute encephalopathy associated with influenza A infection in 3 adults. We detected high cerebrospinal fluid (CSF) and plasma concentrations of CXCL8/IL-8 and CCL2/MCP-1 (CSF/plasma ratios > or =3), and interleukin-6, CXCL10/IP-10, but no evidence of viral neuroinvasion. Patients recovered without sequelae. Hyperactivated cytokine response may play a role in pathogenesis.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874350PMC
http://dx.doi.org/10.3201/eid1601.090007DOI Listing

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