Syphilis reemerged in Martinique in 2004 and initially affected 3 HIV-infected patients. By March 2008, syphilis was diagnosed for 37 men and 18 women. As of October 31, 2009, this outbreak had not yet been brought under control. It initially affected mainly men who had sex with men before it spread to heterosexual persons, minority group members, and crack cocaine users.
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http://dx.doi.org/10.3201/eid1601.081730 | DOI Listing |
Histopathology
December 2024
University of Virginia Health System, Charlottesville, VA, USA.
The resurgence of measles, syphilis, and HIV presents a significant threat to global health, especially in the wake of the COVID-19 pandemic. These three infections involve lymph nodes and have unique pathologic findings in lymph nodes. We explore the pathological and clinical characteristics of these infections, focusing on their involvement of lymph nodes and their pathologic diagnosis in lymph node specimens.
View Article and Find Full Text PDFSex Transm Infect
December 2024
Department of Science and Promotion of Health G D'Alessandro, University of Palermo, Palermo, Sicilia, Italy
Syphilis is a re-emerging disease, and suspicion of syphilis infection should be considered in all cases with atypical skin manifestations, mainly when there is a history of unprotected sexual intercourse. Here, we describe a case of secondary syphilis in a woman aged 42 years, who presented with an atypical, painful and itchy skin rash with vegetative cerebriform lesions, which resolved after the administration of penicillin. Multiplex PCR targeting on vaginal and lesion swabs, along with syphilis serology, confirmed the diagnosis.
View Article and Find Full Text PDFPathogens
November 2024
Department of Pediatrics, University of British Columbia, A5-179, 950 West 28th Ave., Vancouver, BC V5Z 4H4, Canada.
Congenital syphilis is a re-emerging infectious threat in areas of North America. The purpose of this study was to quantitatively describe the rate of decline of nontreponemal (rapid plasma reagin, RPR) titers in pregnant persons with syphilis and their infants. In a retrospective review, we included 120 pregnant persons with 563 reactive RPR measurements (median 5, range 2 to 11 per person) and 35 infants with 81 RPR measurements (median 2, range 2 to 6 per infant).
View Article and Find Full Text PDFR I Med J (2013)
December 2024
Department of Medicine, Division of Infectious Disease and Division of Obstetric Medicine, Warren Alpert Medical School of Brown University, Women & Infants Hospital, Providence, RI.
Syphilis, once in decline, is seeing a rapid re-emergence throughout the United States. A sexually transmitted infection caused by the spirochete Treponema pallidum, syphilis infection in pregnancy can result in serious complications and have a profound impact on maternal and neonatal health. As rates of syphilis have increased among people of reproductive age, so too have cases of congenital syphilis.
View Article and Find Full Text PDFClin Ophthalmol
October 2024
Department of Ophthalmology, Unidade Local de Saúde de São João, Porto, Portugal.
Purpose: Syphilis is a re-emerging infectious disease with various systemic manifestations, including ocular involvement, which can lead to significant morbidity if untreated. This study aims to analyze the ocular manifestations of syphilis in patients treated at a Portuguese tertiary center over a 14-year period.
Patients And Methods: A retrospective review of patients diagnosed with syphilis who presented with ocular symptoms from 2010 to 2023 was conducted.
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