AI Article Synopsis
- Scientists have created a new way to make special chemicals called cis-trisubstituted vinylaziridines, which are used in medicine and chemistry.
- This new method combines two steps done together: one involves a reaction with sulfur to create a ring structure, and the other uses a metal called palladium to change the structure slightly.
- This process is really good at making the desired result, which means they are likely to get the right chemical every time they try it!
Article Abstract
Highly diastereoselective synthesis of cis-trisubstituted vinylaziridines containing a quaternary carbon center is realized by a one-pot protocol in which the combination of sulfur ylide-mediated aziridination of cyclic ketimines and Pd(0)-catalyzed isomerization is employed successfully.
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| http://dx.doi.org/10.1021/ol9027072 | DOI Listing |
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