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An Exploratory Study of PN HPT for Treating Postsurgical Atrophic and Depressed Scars.
J Cosmet Dermatol
January 2025
Clinical Pharmacology Consultant in Aesthetic Medicine, Milan, Italy.
Background: Postsurgical atrophic scars tend to respond poorly to treatments, especially non-energy-based ones. Hydrophilic PN HPT (Polynucleotides High Purification Technology) injected intradermally is a non-energy-based option with an immediate volume-enhancing effect that indirectly improves the fibroblast synthesis of collagen and extracellular matrix. The PN HPT ingredient has the further benefit of a dermal "priming" effect that enhances the efficacy of other scar treatments.
View Article and Find Full Text PDFImpact of Needle-Free Connector and Prefilled Flushing Syringe Shortage on CLABSI Rates in Pediatric Intensive Care.
Infect Dis Clin Microbiol
December 2024
Department of Pediatric Intensive Care Unit, Dr. Behçet Uz Children's Diseases and Surgery Training and Research Hospital, İzmir, Türkiye.
Objective: We aimed to discuss our experience of a higher incidence of catheter-associated bloodstream infections (CLABSIs) during the needle-free connector (NFC) and single-use prefilled flushing syringe (PFS) shortage.
Materials And Methods: Retrospective analyses were carried out to investigate the CLABSI rates at a tertiary training hospital from January 1, 2023, to December 31, 2023, and the study period included a three-month shortage of NFCs and PFSs in April and June 2023.
Results: The CLABSI rate for the three months was 5.
Microplastics in different nasal irrigation options.
Eur Arch Otorhinolaryngol
January 2025
Department of Otorhinolaryngology, Medical Faculty, Kırıkkale University, Kırıkkale, Turkey.
Purpose: We aimed to assess the presence of microplastics in nasal irrigation methods commonly used in the treatment of sinusitis and rhinitis, and to evaluate human exposure.
Methods: A total of 150 samples were included in the study, consisting of nasal wash bottles containing nasal irrigation solution, seawater spray, syringes for nasal irrigation with isotonic solution. The amount of microplastics per millilitre in the samples and patient exposure during single use were assessed separately for each method and product.
Quantitative Monitoring Maximizes Cost-Saving Strategies When Antagonizing Neuromuscular Block With Sugammadex.
Cureus
September 2024
Department of Anesthesiology, University of Colorado, Aurora, USA.
Introduction Weight-based dosing combined with variable patient weights in pediatric anesthesia can lead to significant medication excess and waste from single-use medication vials packaged for dosing in adults. Medication aliquots have been proposed as a strategy to decrease waste and therefore expense when using high-cost medications such as sugammadex. Appropriate dosing of sugammadex to antagonize neuromuscular block is based on the results of quantitative monitoring, though the use of these monitors is not routine.
View Article and Find Full Text PDFDirect in-scope suction: an in vitro evaluation of a single use flexible ureteroscope with integrated suction capability.
World J Urol
September 2024
GRC n°20, Groupe de Recherche Clinique sur la Lithiase Urinaire, Hôpital Tenon, Sorbonne Université, 75020, Paris, France.
Purpose: To evaluate the stone clearance rate and limitations of a novel integrated suction capability within a single-use flexible ureteroscope according to stone particle size.
Methods: Varying sized stone particles were created using a stone phantom (Begostone Plus, Bego ©, Lincoln, RI, USA). Particle size ranged as follows: 63-125 µm, 125-250 µm, 250-500 µm, 500 µm- 1 mm and 1-2 mm.
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