We studied clinical efficiency and IFN-inducing activity of anaferon in chronic recurrent genital herpes with high incidence of relapses. The use of anaferon in complex therapy reduced the duration of intoxication symptoms and local symptoms, shortened the duration of the relapse, activated expression of IFN-gamma mRNA, and improved IFN-gamma-producing capacity of blood leukocytes.
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Adjunctive use of interferon γ inducer for treatment of patients with schizophrenia.
Acta Neuropsychiatr
June 2016
4Endogenous Disorders Department, Mental Health Research Institute,Tomsk,Russian Federation.
Article Synopsis
- - The study evaluated the clinical and immunomodulatory effects of an ultra-high dilution drug, anaferon, in 40 schizophrenia patients, compared to a placebo group, over a 30-day treatment period.
- - Results indicated that patients taking anaferon showed an increase in spontaneous interferon γ production and improved psychopathological symptoms, compared to those receiving a placebo.
- - The findings suggest that anaferon may enhance treatment efficacy for schizophrenia through a mechanism of psychoimmunomodulation by increasing immune response.
Complex application of preparation containing ultralow doses of antibodies for the treatment of anemia caused by pubertal uterine bleedings.
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Institute of Pharmacology, Tomsk Research Center, Siberian Division of Russian Academy of Medical Sciences, Tomsk.
Poetam and anaferon (pediatric formulation) administered in combination with iron preparation to patients with anemia induce pronounced positive shifts in metabolic and morphological status of mature erythrocytes: the number of sulfhydryl groups and lipoprotein complexes in cell membranes and dry weight of erythrocytes increased, while the number of forms at different stages of degeneration decreased.
View Article and Find Full Text PDFAnaferon-supplemented complex therapy of chronic recurrent genital herpes reduced clinical symptoms of the disease and normalized the content of immunocompetent cells. Changes in the level of immunocompetent cells depended on the severity of genital herpes.
View Article and Find Full Text PDFEfficiency of anaferon in complex therapy of genital herpes.
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Institute of Immunology, Federal Biomedical Agency, Moscow.
We studied clinical efficiency and IFN-inducing activity of anaferon in chronic recurrent genital herpes with high incidence of relapses. The use of anaferon in complex therapy reduced the duration of intoxication symptoms and local symptoms, shortened the duration of the relapse, activated expression of IFN-gamma mRNA, and improved IFN-gamma-producing capacity of blood leukocytes.
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Comparative placebo-controlled clinical trials on the efficiency and safety of ultralow doses of antibodies to human IFN-gamma (anaferon pediatric formulation and anaferon) and prophylaxis of bacterial complication showed that administration of these preparations in complex therapy of bacterial infection reduced the incidence of bacterial complications of viral infections and considerably decreased the duration of the main clinical symptoms of the disease.
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