Prophylactic efficiency and safety of anaferon (pediatric formulation) in children aging 1?month to 4 years, including sickly children, was proven. The use of the preparation in children reduced the incidence of acute respiratory infections, alleviated the course of the disease, and decreased the incidence of detection of viral antigens in nasal meatuses.
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[The efficacy of anti-viral therapy and serotherapy of tick-borne encephalitis in children].
Zh Nevrol Psikhiatr Im S S Korsakova
November 2019
Children's Research and Clinical Center for Infectious Diseases, St. Petersburg, Russia.
Objective: To evaluate the efficacy of different methods of antivirus therapy of tick-borne encephalitis (TBE) in children in the acute period and during chronic infections.
Material And Methods: During 1 year, 130 children, aged 7-17 years, with TBEV received therapy in the acute period (an average in 3.5±1.
Anaferon and pediatric anaferon based on release-active antibodies to interferon-gamma (R-A antibodies to INF-gamma) proved to be efficient in the treatment of many viral infections. Immunomodulating (immunotropic) properties of the drugs were revealed in the preclinical studies at many Russian and foreign research medical institutions and are reviewed herein. Anaferon and pediatric anaferon stimulated the humoral and cellular immune responses and increased the neutrophil and macrophage activity.
View Article and Find Full Text PDF[Study of efficacy of anaferon pediatric in mice infected by pandemic influenza virus A(H1N1/09)v].
Zh Mikrobiol Epidemiol Immunobiol
May 2011
Aim: To study efficacy of anaferon pediatric in mice infected by pandemic influenza virus A(H1N1/09)v.
Materials And Methods: Influenza virus strain A/California/07/2009 (H1N1)v was used. Three groups of BALB/c mice intranasally inoculated with influenza virus were studied.
Antiviral activity of Anaferon (pediatric formulation) in mice infected with pandemic influenza virus A(H1N1/09).
Bull Exp Biol Med
October 2010
Vector Research Center of Virology and Biotechnology, Federal Service on Surveillance for Consumer Rights Protection and Human WellBeing, Kol'tsovo, Novosibirsk Region, Russia.
Article Synopsis
- Anaferon, a pediatric formulation, showed antiviral effects in mice infected with the H1N1 virus, significantly reducing virus production in their lungs.
- Anaferon was administered both therapeutically and prophylactically, leading to a 10-fold decrease in viral load compared to control mice.
- Its effectiveness was comparable to Tamiflu when given before or after the infection.
Complex application of preparation containing ultralow doses of antibodies for the treatment of anemia caused by pubertal uterine bleedings.
Bull Exp Biol Med
September 2009
Institute of Pharmacology, Tomsk Research Center, Siberian Division of Russian Academy of Medical Sciences, Tomsk.
Poetam and anaferon (pediatric formulation) administered in combination with iron preparation to patients with anemia induce pronounced positive shifts in metabolic and morphological status of mature erythrocytes: the number of sulfhydryl groups and lipoprotein complexes in cell membranes and dry weight of erythrocytes increased, while the number of forms at different stages of degeneration decreased.
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