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  • Epiglottitis is an inflammation of the epiglottis that can cause airway obstruction, previously mostly affecting children due to Hib infections, but now more common in adults following widespread vaccinations.
  • A case of a fully vaccinated 58-year-old woman revealed severe symptoms and a successful bedside nasopharyngoscopy by emergency medicine, preventing the need for intubation.
  • The report emphasizes recognizing epiglottitis in adults, the role of emergency physicians in performing nasopharyngoscopy, and the effectiveness of early treatment with antibiotics and corticosteroids for better recovery outcomes.
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Article Synopsis
  • The COVID-19 pandemic has significantly impacted global health and economies, leading to the launch of numerous clinical trials to evaluate the effectiveness of various therapeutic agents.
  • The text discusses different COVID-19 treatments, such as antiviral agents, tocilizumab, JAK inhibitors, neutralizing antibodies, and corticosteroids, as well as the effectiveness of COVID-19 vaccines like mRNA, viral vector, inactivated, and protein subunit types.
  • The emergence of new variants complicates clinical data interpretation, emphasizing the ongoing need for therapeutic agents while also underscoring the importance of assessing vaccine efficacy against diverse strains.
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Background: The current study attempted to replicate the original findings regarding the effects of power posing on testosterone and cortisol levels, risk-taking behavior, and perceived power. We further extended the investigation by testing the effect of power posing on estradiol and progesterone levels.

Methods: A sample of 92 young adults (30 males; 32 females taking oral contraceptives; and 30 females not taking oral contraceptives who were in their midluteal phase) were randomly assigned to high-power-pose or low-power-pose conditions and asked about their feelings of power.

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Objective: To review and synthesize the available evidence for use of perioperative systemic steroids for otolaryngologic surgical procedures.

Data Sources: A comprehensive literature review with evidence-informed recommendations.

Review Methods: Databases were queried for medical subject heading terms and keywords related to perioperative systemic corticosteroids use for comprehensive otolaryngology and subspecialty procedures including otologic, sinonasal, sleep, laryngeal, head and neck, facial plastics, and pediatric surgery.

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Clinical Guidelines for Management of Infants Born before 25 Weeks of Gestation: How Representative Is the Current Evidence?

J Pediatr

November 2024

Newborn Services and Newborn Research, Royal Women's Hospital, Melbourne, Australia; Department of Obstetrics, Gynaecology and Newborn Health, The University of Melbourne, Melbourne, Australia; Department of Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Australia.

Article Synopsis
  • - The study evaluates if major management guidelines for extremely preterm infants are effectively applicable to those born before 25 weeks' gestation by reviewing three significant sets of guidelines and their referenced studies.
  • - Out of 519 studies analyzed, only about 14.5% of infants were under 25 weeks, with a significant portion of the research, 37.8%, not including any infants from this critical group.
  • - The findings conclude that infants born before 25 weeks gestation are underrepresented in the data driving clinical guidelines, highlighting the need for more focused research on this vulnerable population.
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