AI Article Synopsis
- 90 community-associated methicillin-resistant S. aureus (CA-MRSA) strains from skin infections were analyzed, all testing positive for mecA, indicating antibiotic resistance.
- 24 strains showed resistance to certain antibiotics and 85 of them expressed a specific serotype.
- Pulsed-field gel electrophoresis identified three main groups of CA-MRSA strains, with the most common group being similar to strains previously found in Uruguay and Brazil, showcasing the persistence of this pathogen over three years.
Article Abstract
We analyzed 90 nonduplicates community-associated methicillin-resistant S. aureus (CA-MRSA) strains isolated from skin and soft-tissue infections. All strains were mecA positive. Twenty-four of the 90 strains showed inducible macrolide-lincosamide-streptogramin B resistance. All strains produced alpha-toxin; 96% and 100% of them displayed positive results for lukS-F and cna genes, respectively. Eigthy-five strains expressed capsular polysaccharide serotype 8. Six different pulsotypes were discriminated by pulsed-field gel electrophoresis (PFGE) and three predominant groups of CA-MRSA strains (1, 2, and 4) were identified, in agreement with phenotypic and genotypic characteristics. Strains of group 1 (pulsotype A, CP8+, and Panton-Valentine leukocidin (PVL)+) were the most frequently recovered and exhibited a PFGE band pattern identical to other CA-MRSA strains previously isolated in Uruguay and Brazil. Three years after the first local CA-MRSA report, these strains are still producing skin and soft-tissue infections demonstrating the stability over time of this community-associated emerging pathogen.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775192 | PMC |
| http://dx.doi.org/10.1155/2009/472126 | DOI Listing |
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