Background/aims: To compare body fat (BF) measurements obtained with a new ultrasound method with those assessed by dual-energy X-ray absorptiometry (DEXA) in obese adolescents.
Methods: In 94 adolescents (57 females and 37 males) aged 12-19 years and body mass index (BMI) exceeding 30 kg.m(-2), the z-score BMI for age was 6.7 (adolescent girls) and 6.6 (adolescent boys) >97th percentile. BF was measured using DEXA and a method based on ultrasound measurements, body weight, height, abdominal circumference and mid-thigh circumference.
Results: Obesity class I was noted in 39%, II in 28% and III in 33% of the patients. BF by ultrasound correlated closely with BF by DEXA, in both females (r = 0.958) and males (r = 0.981), with standard errors of the estimates (SEE) being 2.9 and 2.5 kg, respectively. The ultrasound method was more accurate than the skinfold technique (n = 24; SEE: 2.2 vs. 6.5 kg, respectively). In 13 adolescents who had marked weight loss after 6 months of treatment, the decrease in DEXA-measured BF correlated closely with the decrease in ultrasound-measured BF (r = 0.95).
Conclusions: Our innovative portable ultrasound technique has advantages in terms of reliability, reproducibility, accuracy and costs for screening and monitoring obese adolescents. A patent application has been submitted. Our method should prove valuable for epidemiological studies.
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http://dx.doi.org/10.1159/000265849 | DOI Listing |
Pol J Vet Sci
December 2024
Department of Animal Welfare and Research, University of Warmia and Mazury in Olsztyn, Oczapowskiego 5, Poland.
Poultry scientists are constantly studying different breeds of cockerels that would be suitable for capon meat production. Capon meat, although not yet very popular, is characterized by exceptional taste qualities that could appeal to many customers. Obtaining the appropriate palatability, structure and tenderness of capon meat is possible thanks to the reduction in androgen levels following the castration of roosters.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
December 2024
Department of Rehabilitation, Jiujiang College Hospital, Jiujiang, Jiangxi, China.
Metabolic diseases have gradually become one of the most significant global medical burdens. Diseases such as obesity, diabetes, and metabolic syndrome, along with their complications, are clinically categorized as metabolic diseases. Long-term oral medication significantly reduces patient compliance and quality of life.
View Article and Find Full Text PDFFront Immunol
December 2024
School of Optometry, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.
Background: Thyroid-associated orbitopathy (TAO) is an autoimmune inflammatory disorder of the orbital adipose tissue, primarily causing oxidative stress injury and tissue remodeling in the orbital connective tissue. Ferroptosis is a form of programmed cell death driven by the accumulation of reactive oxygen species (ROS), iron metabolism disorder, and lipid peroxidation. This study aims to identify and validate the optimal feature genes (OFGs) of ferroptosis with diagnostic and therapeutic potential in TAO orbital adipose tissue through bioinformatics analysis and to assess their correlation with disease-related immune cell infiltration.
View Article and Find Full Text PDFeGastroenterology
October 2024
Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Alcohol-associated liver disease (ALD) is a growing global health concern and its prevalence and severity are increasing steadily. While bacterial endotoxin translocation into the portal circulation is a well-established key factor, recent evidence highlights the critical role of sterile inflammation, triggered by diverse stimuli, in alcohol-induced liver injury. This review provides a comprehensive analysis of the complex interactions within the hepatic microenvironment in ALD.
View Article and Find Full Text PDFTransgend Health
December 2024
Andrology Unit, Department of Clinical Medicine, Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
Purpose: There is a paucity of data on the safety and efficacy of long-term testosterone (T)-based gender-affirming hormone therapy (GAHT) on anthropometric parameters, body composition, and glycolipid metabolism in assigned female at birth (AFAB) persons. The purpose of this study was to provide an updated meta-analysis on this topic.
Methods: We searched PubMed, Scopus, and Cochrane Library for relevant studies.
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