AI Article Synopsis
- Recombination of homologous chromosomes is crucial for the proper segregation of chromosomes during meiosis.
- Different organisms use various strategies for this process, which involves two key steps: aligning homologous chromosomes and recognizing their partners.
- The text reviews the mechanisms involved in both the alignment and recognition phases during meiosis.
Article Abstract
Recombination of homologous chromosomes is essential for correct reductional segregation of homologous chromosomes, which characterizes meiosis. To accomplish homologous recombination, chromosomes must find their homologous partners and pair with them within the spatial constraints of the nucleus. Although various mechanisms have developed in different organisms, two major steps are involved in the process of pairing: first, alignment of homologous chromosomes to bring them close to each other for recognition; and second, recognition of the homologous partner of each chromosome so that they can form an intimate pair. Here, we discuss the various mechanisms used for alignment and recognition of homologous chromosomes in meiosis.
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| http://dx.doi.org/10.1111/j.1742-4658.2009.07501.x | DOI Listing |
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