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Prospective study of exclusive strontium-/yttrium-90 beta-irradiation of primary and recurrent pterygia with no prior surgical excision. Clinical outcome of long-term follow-up. | LitMetric

AI Article Synopsis

  • The study aimed to assess the effectiveness of strontium-yttrium-90 beta-irradiation in treating both primary and recurrent pterygia, focusing on recurrence rates and functional outcomes.
  • Over a follow-up period averaging nearly 47 months, the treatment successfully reduced the size of all pterygia without any reported recurrences or side effects and improved visual acuity and astigmatism.
  • The findings suggest that this beta-irradiation treatment is efficient and well-tolerated, offering better aesthetic and rehabilitative outcomes compared to traditional methods, particularly for recurrent cases after surgery.

Article Abstract

Purpose: To evaluate the consecutive treatment results regarding pterygium recurrence and the efficacy of exclusive strontium-/yttrium-90 beta-irradiation for primary and recurrent pterygia and to analyze the functional outcome.

Patients And Methods: Between October 1974 and December 2005, 58 primary and 21 recurrent pterygia were exclusively treated with strontium-/yttrium-90 beta-irradiation with doses ranging from 3,600 to 5,500 cGy. The follow-up time was 46.6 +/- 26.7 months, with a median of 46.5 months.

Results: The treatment led to a size reduction in all pterygia (p < 0.0001). Neither recurrences nor side effects were observed during therapy and follow-up in this study. Best-corrected visual acuity increased (p = 0.0064). Corneal astigmatism was reduced in recurrent pterygia (p = 0.009).

Conclusion: Exclusive strontium-/yttrium-90 beta-irradiation of pterygia is a very efficient and well-tolerated treatment, with remarkable aesthetic and rehabilitative results in comparison to conventional treatments, especially for recurrent lesions which have undergone prior surgical excision.

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Source
http://dx.doi.org/10.1007/s00066-009-2000-1DOI Listing

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