The aim of the present work was to identify complex morphometric characteristics of the living brain in children aged one year with assessment of individual variation (sexual, interhemisphere) by magnetic resonance tomography. The results demonstrated sexual dimorphism in brain sizes: endbrain sizes were generally larger in boys, while structures in the stem part of the brain were larger in girls. Interhemisphere asymmetry of the brain was found in one-year-old children - in most cases, lobe sizes were greater in the right hemisphere as compared with the left.
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http://dx.doi.org/10.1007/s11055-009-9224-5 | DOI Listing |
Anat Histol Embryol
January 2025
Department of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
This study investigates the gross morphological and morphometric characteristics of thoracic and lumbar intervertebral discs (IVDs) in guinea pigs, utilising micro-CT imaging and anatomical dissection. The findings reveal 13 thoracic and six lumbar IVDs were identified, with thoracic discs transitioning from rounded forms at T1-T3 to triangular and heart-shaped structures at T4-T13, while lumbar IVDs exhibited a consistently flattened heart shape. Morphometric analysis revealed statistically significant differences, with lumbar IVDs being larger in lateral and dorsoventral width, disc area, annulus fibrosus (AF) area and nucleus pulposus (NP) area, and ventral height compared to thoracic discs.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Amsterdam UMC, Amsterdam, Netherlands
Background: The Amyloid Imaging to Prevent Alzheimer’s Disease (AMYPAD) Prognostic & Natural History Study (PNHS) is a prospective longitudinal PET cohort of over 1,500 non‐demented individuals from 10 parent cohorts across Europe. We provide an overview of ongoing efforts to curate and integrate magnetic resonance imaging (MRI) multimodal images across sites and to extract biologically meaningful information (, image‐derived phenotypes; IDPs) in this early AD population. Data will be made available on the ADDI platform (fair.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Xuanwu Hospital, Capital Medical University, Beijing, China
Background: Graph theory is an advanced method for analyzing the balance of brain networks. However, the changes in white matter (WM) and metabolic networks and their correlation with clinical features in patients with posterior cortical atrophy (PCA) require further investigation. This study aims to clarify the structural, metabolic, WM, and metabolic topological network in PCA, and explore their correlation with clinical features.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
Background: Regional brain atrophy estimated from structural MRI is the most widely used measure of neurodegeneration in Alzheimer’s disease (AD), Frontotemporal Lobar Degeneration (FTLD), and other dementias. Yet, traditional MRI‐derived morphometric estimates are susceptible to measurement errors, posing a challenge for reliably detecting longitudinal atrophy, particularly over short intervals. We examined the utility of multiple accelerated MRI scans acquired in rapid succession (i.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
UCLA, Los Angeles, CA, USA
Background: Predictive biomarkers characterizing disease progression are called for in the context of emerging treatments for Alzheimer’s disease. We implemented a link prediction model on morphometric correlation networks(MCN) generated from structural MRI.
Method: High‐resolution T1MPRAGE images were retrospectively collected at two timepoints (interval 2.
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