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Pharmacologic Adjuncts for Neonatal Tracheal Intubation: The Evidence Behind Premedication.
Neoreviews
December 2023
Department of Pediatrics, Division of Neonatology, University of Colorado School of Medicine and Children's Hospital of Colorado, Denver, CO.
Article Synopsis
- - Premedication for neonatal tracheal intubation, including analgesia, sedation, and paralytics, can enhance success rates and minimize risks associated with the procedure.
- - This review covers various premedication classes, their indications, administration routes, dosages, and potential side effects in different infant populations.
- - The article highlights the need for guidelines on premedication, especially with the rise in survival of extremely preterm infants, and addresses gaps in established practices during certain medical procedures.
Vasovagal Responses to Human Monomorphic Ventricular Tachycardia: Hemodynamic Implications From Sinus Rate Analysis.
J Am Coll Cardiol
September 2023
University of Arizona College of Medicine, Banner-University Medical Center, Division of Cardiology, Phoenix, Arizona, USA. Electronic address:
Background: Factors determining hemodynamic stability during human ventricular tachycardia (VT) are incompletely understood.
Objectives: The purposes of this study were to characterize sinus rate (SR) responses during monomorphic VT in association with hemodynamic stability and to prospectively assess the effects of vagolytic therapy on VT tolerance.
Methods: This is a retrospective analysis of patients undergoing scar-related VT ablation.
Ketamine Use in the Intubation of Critically Ill Children with Neurological Indications: A Multicenter Retrospective Analysis.
Neurocrit Care
February 2024
Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Background: Ketamine has traditionally been avoided for tracheal intubations (TIs) in patients with acute neurological conditions. We evaluate its current usage pattern in these patients and any associated adverse events.
Methods: We conducted a retrospective observational cohort study of critically ill children undergoing TI for neurological indications in 53 international pediatric intensive care units and emergency departments.
Association of full premedication on tracheal intubation outcomes in the neonatal intensive care unit: an observational cohort study.
J Perinatol
August 2023
University of Washington School of Medicine and Seattle Children's Hospital, Department of Pediatrics, Division of Neonatology, Seattle, WA, USA.
Objective: Evaluate the association of short-term tracheal intubation (TI) outcomes with premedication in the NICU.
Study Design: Observational single-center cohort study comparing TIs with full premedication (opiate analgesia and vagolytic and paralytic), partial premedication, and no premedication. The primary outcome is adverse TI associated events (TIAEs) in intubations with full premedication compared to those with partial or no premedication.
Transient asystole during balloon dilation of the Eustachian tube: A case report.
Medicine (Baltimore)
November 2022
Department of Anesthesiology and Pain Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Article Synopsis
- Neurally mediated reflexes can cause cardiac arrest during head and neck surgery, but balloon dilation of the Eustachian tube (BDET) is generally safe and rarely leads to serious complications.
- A 33-year-old woman experienced transient asystole (13 seconds) during BDET when the balloon was inflated under general anesthesia.
- Following deflation of the balloon and the administration of vagolytic drugs, the patient returned to normal rhythm and recovered well after the procedure, highlighting the need for careful monitoring by both anesthesiologists and otolaryngologists.*
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