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Automatic Detection of Cognitive Impairment in Patients With White Matter Hyperintensity Using Deep Learning and Radiomics.
Am J Alzheimers Dis Other Demen
March 2025
Pathology Department, Chongqing UniversityCentral Hospital, Chongqing Emergency Medical Center, Chongqing, China.
White matter hyperintensity (WMH) is associated with cognitive impairment. In this study, 79 patients with WMH from hospital 1 were randomly divided into a training set (62 patients) and an internal validation set (17 patients). In addition, 29 WMH patients from hospital 2 were used as an external validation set.
View Article and Find Full Text PDFPredicting pathological tumor volume in prostate cancer lesions: A head-to-head comparison of micro-ultrasound vs. MRI.
Urol Oncol
March 2025
Department of Urology, Lausanne University Hospital, Lausanne, Switzerland. Electronic address:
Background And Objective: Our objective was to evaluate the agreement between micro-ultrasound, MRI and pathological tumor and prostate volume.
Methods: Retrospective analysis of consecutive prostate cancer patients with MRI and micro-ultrasound diagnostic assessment who subsequently underwent radical prostatectomy. Tumor and prostate volume on micro-ultrasound and MRI imaging calculated by a dedicated software were compared to those of the prostatectomy specimen.
Time efficiency and precision of splinted complete arch implant scanning.
J Prosthet Dent
March 2025
Associate Professor, Department of Restorative Dentistry, Faculty of Dentistry, Universiti Malaya, Kuala Lumpur, Malaysia. Electronic address:
Statement Of Problem: The precision and accuracy of intraoral scanners for complete arch implant scanning is questionable as it is affected by the absence of anatomic features, the presence of large homogenous areas, and the lack of clear reference points, all of which create inherent errors in the image stitching process by the scanner software program.
Purpose: The purpose of this in vitro study was to test a newly designed scan-aid apparatus for evaluating the effect of geometric heterogeneity and additional reference points on the time efficiency and scanning precision of complete arch implant scanning.
Material And Methods: A total of 60 scans (20 per group) were performed using an intraoral scanner in 3 different clinical simulations: 2 parallel implants, 4 parallel implants, and 4 implants; 2 anterior implants in parallel axial orientation; and 2 distal implants with a 30-degree posterior inclination.
Delivering Gd-Labeled IgG Antibodies Into the Mouse Brain Following Focused Ultrasound Treatment.
Ultrasound Med Biol
March 2025
School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK. Electronic address:
Objective: Antibody-based therapy has emerged as a powerful tool for targeted treatment of neurological diseases, such as brain cancer and neurodegenerative disorders. However, direct, scalable, and safe confirmation of antibody delivery into the brain remains challenging. Antibodies can be effectively tracked when tagged with molecules that are detectable by medical imaging modalities, such as MRI, PET, or SPECT.
View Article and Find Full Text PDFImaging in sarcoid disease.
Best Pract Res Clin Rheumatol
March 2025
Department of Radiology, Mayo Clinic, 200 1st St SW, Rochester, MN, 55902, USA. Electronic address:
Sarcoidosis is a complex multisystem inflammatory disease characterized by noncaseating granulomas and variable clinical manifestations, most commonly affecting the lungs, skin, heart, and nervous system. Imaging is central in its diagnosis, staging, and management, providing essential insights into organ involvement and disease activity. Pulmonary manifestations remain the hallmark, with modalities such as high-resolution chest computed tomography (CT) and chest radiography offering critical diagnostic clues.
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