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Detection of equine influenza virus gene in the air around infected horses.
Vet Microbiol
January 2025
Equine Research Institute, Japan Racing Association, Shimotsuke, Tochigi, Japan.
Equine influenza virus (EIV) can be transmitted by inhalation of aerosolized droplets, direct contact, and contaminated fomites. However, to our knowledge, there are no reports of the recovery of EIV from the air surrounding infected horses. Here, we evaluated whether EIV can be recovered from the air in the stalls of experimentally infected horses by using an air sampler.
View Article and Find Full Text PDFEvolutionary characterization of the establishment of H6 influenza viruses in domestic geese in China: implications for the position of the host in the ecosystem.
Virus Evol
September 2024
Guangdong-Hong Kong Joint Laboratory of Emerging Infectious Diseases/Joint Laboratory for International Collaboration in Virology and Emerging Infectious Diseases, Joint Institute of Virology (STU/HKU), Shantou University Medical College, Shantou University, 243 Daxue Road, Shantou, Guangdong 515063, China.
Geese, both wild and domestic, are generally considered part of the natural reservoir for influenza A viruses. The highly pathogenic H5 Goose/Guangdong avian influenza virus lineage that is still causing outbreaks worldwide was first detected in domestic geese in 1996. However, while wild geese might have a somewhat restricted role in the influenza ecosystem, the role of domestic geese is little studied.
View Article and Find Full Text PDFAdvantages of Broad-Spectrum Influenza mRNA Vaccines and Their Impact on Pulmonary Influenza.
Vaccines (Basel)
December 2024
Division of HIV/AIDS and Sex-Transmitted Virus Vaccines, National Institutes for Food and Drug Control (NIFDC), Beijing 102629, China.
Influenza poses a significant global health challenge due to its rapid mutation and antigenic variability, which often leads to seasonal epidemics and frequent outbreaks. Traditional vaccines struggle to offer comprehensive protection because of mismatches with circulating viral strains. The development of a broad-spectrum vaccine is therefore crucial.
View Article and Find Full Text PDFMammalian ZAP and KHNYN independently restrict CpG-enriched avian viruses.
bioRxiv
December 2024
Department of Microbiology and Immunology, University of Minnesota - Twin Cities, Minneapolis, MN, USA, 55455.
Zoonotic viruses are an omnipresent threat to global health. Influenza A virus (IAV) transmits between birds, livestock, and humans. Proviral host factors involved in the cross-species interface are well known.
View Article and Find Full Text PDFMortality causes and health spending by gender and health conditions in octogenarians, nonagenarians and centenarians in Colombia.
Sci Rep
January 2025
School of Public Health, University Medical Center Utrecht, Utrecht University & Harvard T.H. Chan, Harvard University, Utrecht, The Netherlands.
This document determines the causes of mortality (2008-2022) and calculate per capita health expenditure (2013-2021) in octogenarians, nonagenarians and centenarians in the Colombian population, considering year, gender and age group. For this nationwide retrospective descriptive observational study, epidemiological regions, urban/rural areas and morbidities were also studied. A mean of 75,552 deaths was observed from 2008 to 2022.
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