AI Article Synopsis

  • The study examined the frequency of the BLyS -817C>T genetic variant in women with deep infiltrating endometriosis or adenomyosis compared to women without endometriosis symptoms and healthy women.
  • Women with deep infiltrating endometriosis were less likely to have the BLyS -817C/T genotype when compared to the reference group.
  • The odds ratio for having this genotype was 0.50, suggesting a significant difference in genetic predisposition among the groups analyzed.

Article Abstract

The prevalence of the BLyS -817C>T polymorphic variant among women with either deep infiltrating endometriosis or adenomyosis compared with a group of gynecologic patients without symptomatic endometriosis and a group of healthy women was assessed in this study. Patients with deep infiltrating endometriosis had less often a BLyS -817C/T genotype as compared with the reference group, with an odds ratio of 0.50 (95% confidence interval 0.27-0.93 versus the C/C genotype).

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Source
http://dx.doi.org/10.1016/j.fertnstert.2009.10.041DOI Listing

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