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http://dx.doi.org/10.1111/j.1442-2042.2009.02407.xDOI Listing

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Article Synopsis
  • A 63-year-old man with a renal transplant and lymphoma undergoing chemotherapy (R-CHOP) developed fever and a widespread pustular rash, which were linked to septicemia.
  • After ruling out other conditions, tests confirmed a methicillin-sensitive Staphylococcus aureus (MSSA) infection, primarily from his infected venous access port.
  • Treatment involved removing the port and using a combination of antibiotics, leading to improvement, highlighting the significance of proper diagnosis and management of similar infections in immunocompromised patients.
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We report a case of disseminated cryptococcosis in a treatment-naïve chronic lymphocytic leukemia (CLL) patient. A 60-year-old man presented with a two-week history of intermittent fevers, frontal headaches, night sweats, weight loss and multiple pink papules on hands and face. Cryptococcemia was found by blood culture unexpectedly.

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Triazole fungicide fluconazole has become the most widely used antifungal agent in the world, mainly because of its ability to penetrate well into body fluids and tissues. However, it has been reported to interact with many drugs and because of its common use, the risk of resistance to fluconazole increases. This calls for new anti-fungal drugs that would be able to replace it.

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