Platelet satellitism.

Eur J Haematol

Department of Haematology, Addenbrooke's Hospital, Cambridge, UK.

Published: April 2010

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http://dx.doi.org/10.1111/j.1600-0609.2009.01386.xDOI Listing

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Platelet satellitism refers to the rosetting of the platelets around white blood cells, mostly neutrophils that could lead to spuriously low platelet counts on automated analyzers. The phenomenon has usually been described in EDTA processed blood samples. We describe the clinical course of a patient with immune thrombocytopenia with platelet satellitism in both EDTA as well as non EDTA processed blood samples.

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Platelet cold agglutination (PCA) is a rare in-vitro phenomenon caused by Immunoglobulin M (IgM) autoantibodies, which results in Ethylenediaminetetraacetic Acid (EDTA) independent pseudo thrombocytopenia (PTCP). Its diagnosis is made based on the peripheral blood smear (PBS) examination and pre-test warming blood sample. Here, a case of PTCP secondary to PCA is presented.

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Platelet Satellitism in a Patient with Bronchial Asthma.

Kathmandu Univ Med J (KUMJ)

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Department of Pathology, Dhulikhel Hospital, Kathmandu University Hospital, Dhulikhel, Kavre, Nepal.

Platelet satellitism is uncommon phenomenon characterized by formation of platelet rosette around polymorphonuclear leucocytes in blood smear prepared from Ethylenediaminetetraacetic acid anticoagulated blood. This phenomenon may cause reporting of spurious thrombocytopenia unless proper examination of blood smears. Here we describe a case of platelet satellitism in a 29 year old female which has been incidentally found on evaluation of eosinophilia in a bronchial asthma patient.

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