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It has been generally accepted that excessive exposure to loud music causes various hearing symptoms (e.g. tinnitus) and consequently leads to a risk of permanent hearing damage, known as noise-induced hearing loss (NIHL). Such potential risk of NIHL due to loud music exposure has been widely investigated in musicians and people working in music venues. With advancements in sound technology and rapid developments in the music industry, increasing numbers of people, particularly adolescents and young adults, are exposing themselves to music on a voluntary basis at potentially harmful levels, and over a substantial period of time, which can also cause NIHL. However, because of insufficient audiometric evidence of hearing loss caused purely by music exposure, there is still disagreement and speculation about the risk of hearing loss from music exposure alone. Many studies have suggested using advanced audiological measurements as more sensitive and efficient tools to monitor hearing status as early indicators of cochlear dysfunction. The purpose of this review is to provide further insight into the potential risk of hearing loss caused by exposure to loud music, and thus contribute to further raising awareness of music induced hearing loss.
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http://dx.doi.org/10.3109/14992020903202520 | DOI Listing |
Arch Gerontol Geriatr
March 2025
College of Applied Health Sciences, University of Illinois Urbana-Champaign, 1206 S 4th St, Champaign, IL, USA. Electronic address:
Background: A growing number of adults are aging with hearing impairments. Late-deafened individuals, who experience severe to profound hearing loss after acquiring spoken language, often face unique communication challenges in everyday activities. Despite these difficulties, little is known about the specific activities and contexts where they occur.
View Article and Find Full Text PDFOrv Hetil
March 2025
3 Maihoub ENT Clinic Aliakmona street 16, Cy-3117, Limassol Ciprus.
Adv Sci (Weinh)
March 2025
Department of Oto-Rhino-Laryngology, West China Hospital of Sichuan University, Chengdu, 610000, China.
Effective research and clinical application in audiology and hearing loss (HL) require the integration of diverse data, yet the absence of a dedicated database impedes understanding and insight extraction in HL. To address this, the Genetic Deafness Commons (GDC) is developed by consolidating extensive genetic and genomic data from 51 public databases and the Chinese Deafness Genetics Consortium. This repository comprises 5 983 613 variants across 201 HL genes, revealing the genetic landscape of HL and identifying six novel mutational hotspots within the DNA-binding domains of transcription factors.
View Article and Find Full Text PDFEur Arch Otorhinolaryngol
March 2025
Otolaryngology Research Center, Department of Otolaryngology-Head and Neck Surgery, Tehran University of Medical Sciences, Imam Khomeini Medical Complex, Tehran, Iran.
Purpose: To evaluate the ototoxicity of povidone iodine (PVP-I) at concentrations of 5% and 10% during tympanoplasty by assessing frequency-specific audiometric outcomes and graft success rates in a large cohort of patients.
Methods: This prospective, triple-blinded, randomized clinical trial enrolled 542 patients undergoing primary tympanoplasty. After excluding patients for inadequate follow-up, 204 ears received 10% PVP-I and 199 ears received 5% PVP-I.
Am J Hum Genet
March 2025
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX, USA. Electronic address:
The CDKL (cyclin-dependent kinase-like) family consists of five members in humans, CDKL1-5, that encode serine-threonine kinases. The only member that has been associated with a Mendelian disorder is CDKL5, and variants in CDKL5 cause developmental and epileptic encephalopathy type 2 (DEE2). Here, we study four de novo variants in CDKL2 identified in five individuals, including three unrelated probands and monozygotic twins.
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