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Immune Cell Characteristics and Infections Associated with Chronic Obstructive Pulmonary Disease (COPD), Asthma, and Interstitial Lung Disease (ILD): A Mendelian Randomization Studies.
Br J Hosp Med (Lond)
January 2025
Department of Infectious Diseases, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Epidemiological studies indicate that the involvement of the immune system in the pathogenesis of infections associated with chronic obstructive pulmonary disease (COPD), asthma, and interstitial lung disease (ILD) remains unclear. This study aims to assess the potential causal link between infections associated with COPD, asthma, or ILD and immune system function. We conducted a two-sample Mendelian randomization analysis using publicly available genome-wide association study (GWAS) datasets.
View Article and Find Full Text PDFA systematic review of outcomes reported in studies to optimise the medication use of patients at hospital discharge.
BMC Health Serv Res
January 2025
Department Pharmaceutical Sciences, University of Basel, Basel, Switzerland.
Introduction: Care transitions, specifically hospital discharge, hold a risk for drug-related problems and medication errors. Effective interventions that optimise medication use during and after transitions are needed, yet there is no standardisation of the outcomes. This literature review aimed at collecting outcomes from studies investigating how to optimise medication use of patients following hospital discharge, and to categorise them, as a first step in the development of a core outcome set.
View Article and Find Full Text PDFDeveloping a comprehensive inventory to define harm reduction housing.
Harm Reduct J
January 2025
Opioid Policy Research Collaborative, Heller School for Social Policy & Management, Brandeis University, Waltham, MA, USA.
Background: The City of Boston has faced unprecedented challenges with substance use amidst changes to the illicit drug supply and increased visibility of homelessness. Among its responses, Boston developed six low threshold harm reduction housing (HRH) sites geared towards supporting the housing needs of people who use drugs (PWUD) and addressing health and safety concerns around geographically concentrated tent encampments. HRH sites are transitional supportive housing that adhere to a "housing first" approach where abstinence is not required and harm reduction services and supports are co-located.
View Article and Find Full Text PDFTransforming healthcare: Saudi Arabia's vision 2030 healthcare model.
J Pharm Policy Pract
January 2025
School of Medical and Life Sciences, Sunway University, Sunway City, Malaysia.
Vision 2030 represents Saudi Arabia's strategic socio-economic plan aimed at promoting economic diversification and enhancing living standards. Launched in April 2016, this vision describes an innovative healthcare plan to improve services and outcomes. The merits and drawbacks of public hospitals' 'Model of Care' are examined in this study.
View Article and Find Full Text PDFUrethra-sparing prostate cancer radiotherapy: Current practices and future insights from an international survey.
Clin Transl Radiat Oncol
March 2025
Department of Radiation Oncology, Oncology Institute of Southern Switzerland, EOC, Bellinzona, Switzerland.
Purpose: In prostate cancer patients, high radiation doses to the urethra have been associated with an increased risk of severe genitourinary toxicity following dose-escalated radiotherapy. Urethra-sparing techniques have emerged as a promising approach to reduce urinary toxicity. This international survey aims to evaluate current global practices in urethra-sparing and explore future directions for the implementation of this technique in external beam radiotherapy (EBRT) for prostate cancer.
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