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Glucocorticoid-Induced Side Effects Cause Oral Lesions in Systemic Lupus Erythematosus: A Case Report.
Int Med Case Rep J
November 2024
Department of Oral Medicine, Faculty of Dentistry, Padjadjaran University, Bandung, Indonesia.
Background: Systemic Lupus Erythematosus (SLE) is a complex autoimmune disease with various complications, making its management difficult. Glucocorticoid not only plays an essential role in the pathogenic therapy of SLE but also causes side effects such as oral lesions, especially when administered long-term or at high doses.
Purpose: This case report aims to describe the management of glucocorticoid-induced side effects that cause oral lesions in SLE patient.
Oral Lesion Management in Juvenile SLE with Hepatosplenomegaly.
Int Med Case Rep J
July 2024
Department of Oral Medicine, Faculty of Dentistry, Padjadjaran University, Bandung, Indonesia.
Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease with unknown etiology resulting in chronic multi-organ inflammation. Juvenile Systemic Lupus Erythematosus (JSLE) is a specific diagnosis of SLE in juvenile, characterized by oral ulceration.
Purpose: This case report attempts to provide information for oral medicine specialists in managing JSLE patients with hepatosplenomegaly.
Local intralesional talimogene laherparepvec therapy with complete local response in oral palatine mucosal melanoma: a case report.
J Med Case Rep
May 2024
Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
Background: Mucosal melanoma, an aggressive type of malignancy different from the cutaneous melanomas commonly seen in the head and neck region, represents < 1% of all malignant melanomas. The pathogenesis of mucosal melanoma is unknown. Targetable mutations commonly seen in cutaneous melanoma, such as in the BRAF and NRAS genes, have a lower incidence in mucosal melanoma.
View Article and Find Full Text PDFOral lesions of systemic lupus erythematosus: A collaborative Latin American study.
Lupus
July 2024
Department of Oral Diagnosis and Pathology, School of Dentistry, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Article Synopsis
- - The study examines oral lesions in systemic lupus erythematosus (SLE) patients from Latin America, highlighting their varied characteristics and challenges in diagnosis, especially when lesions appear alone.
- - In a sample of 70 SLE patients, the majority were white females with an average age of 38.4 years, and the most common oral lesions were ulcers, erosions, and white lesions, often found in the hard/soft palate.
- - Findings suggest that unusual oral changes may signal underlying systemic issues, emphasizing the need for a multidisciplinary approach and regular oral exams to identify and treat these lesions effectively.
Oral lesions in adult- and juvenile-onset systemic lupus erythematosus patients: A case series report.
Dent Med Probl
March 2024
Oral Medicine Department, Faculty of Dentistry, Universitas Padjajaran, Bandung, Indonesia.
Article Synopsis
- Systemic lupus erythematosus (SLE) is an autoimmune disease that can lead to various oral manifestations, such as ulcerations, keratotic plaques, and lesions that may resemble conditions like oral lichen planus.
- Recognizing these oral signs is crucial for proper patient management and was explored through four cases in a clinical setting, involving both adults and juveniles with SLE.
- Each patient displayed different oral lesions based on disease severity, and they were treated with antimicrobial therapy, showing positive outcomes.
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