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Association between age at loss of ambulation and cardiac function in adults with Duchenne muscular dystrophy.
Neuromuscul Disord
January 2025
John Walton Muscular Dystrophy Research Centre, Newcastle University, Newcastle upon Tyne, UK; Newcastle Hospitals NHS Foundation Trusts, Newcastle upon Tyne, UK. Electronic address:
Cardiomyopathy is a common co-morbidity in individuals with Duchenne muscular dystrophy (DMD). This retrospective single centre study investigated the relationship between age at loss of ambulation (LOA) and late stage left ventricular ejection fraction (LVEF) in 84 individuals (> 16 years old) with DMD taking glucocorticoid and ACE inhibitors treatment. Regression analyses showed a positive correlation between later age at LOA and higher LVEF in adulthood (linear regression estimate 1.
View Article and Find Full Text PDFReproducibility of fetal ultrasound doppler parameters used for growth assessment.
Arch Gynecol Obstet
January 2025
Fetal Medicine Unit, Elizabeth Garrett Anderson Wing, University College London Hospitals NHS Foundation Trust, 250 Euston Road, London, NW1 2BU, UK.
Objectives: To produce standards of references for quality control and assess the reproducibility of fetal ultrasound Doppler measurements commonly used for blood flow assessment in fetal growth.
Methods: Women with singleton normal pregnancies were prospectively recruited at University College London Hospital, UK, between 24 and 41 weeks. Umbilical artery (UA), middle cerebral artery (MCA), and their pulsatility indices (PI), resistance indices (RI) and ratios such as cerebro-placental (CPR) and umbilical cerebral ratio (UCR) were obtained twice by two sonographers in training or after completion of training, blind to each other's measurements.
Bland-Altman plot to assess the consistency of arterial and venous blood lactate in the emergency room: a retrospective cohort study.
Sci Rep
January 2025
Emergency Trauma Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830000, China.
To measure the correlation and agreement between arterial and peripheral venous blood lactate in the emergency room and to assess the predictive value of lactate for the occurrence of cardiac arrest. This was a retrospective cohort study involving 784 patients from January 1, 2020, to July 31, 2021, in the Emergency Room of the First Affiliated Hospital of Xinjiang Medical University. General information, vital signs, clinical symptoms, and laboratory findings of the patient were collected.
View Article and Find Full Text PDFGastrin-Releasing Peptide Receptor Targeting PET/CT With 68Ga-NOTA-RM26 in the Assessment of Glioma and Combined Multiregional Biopsies.
Clin Nucl Med
January 2025
From the Department of Nuclear Medicine, State Key Laboratory of Complex Severe and Rare Diseases, Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Purpose: The aim of this study was to investigate the value of 68Ga-NOTA-RM26 (68Ga-RM26), a gastrin-releasing peptide receptor-targeting antagonist labeled with the radionuclide 68Ga, in the diagnosis of high-grade gliomas and in combination with multiregional biopsies using PET/CT.
Patients And Methods: After institutional review board approval and informed consent, a total of 35 patients with suspected glioma lesions were enrolled in this study. All patients underwent 68Ga-RM26 PET/CT scans within 2 weeks before surgery.
Investigating eating architecture and the impact of the precision of recorded eating time: a cross-sectional study.
Am J Clin Nutr
January 2025
Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. Electronic address:
Background: The precision of recorded eating times directly affects the estimation of eating architecture i.e. size, timing, and frequency of eating.
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