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Development and optimization of raloxifene hydrochloride loaded lipid nanocapsule based hydrogel for transdermal delivery.
Ther Deliv
January 2025
Institute of Pharmaceutical Research, GLA University, Mathura, India.
Aim: Development and optimization of raloxifene hydrochloride loaded lipid nanocapsule hydrogel for transdermal delivery.
Method: A 3 Box-Behnken Design and numerical optimization was performed to obtain the optimized formulation. Subsequently, the optimized raloxifene hydrochloride loaded lipid nanocapsule was developed using phase inversion temperature and characterized for physicochemical properties.
Understanding the Support Needs of People with Autosomal Dominant Polycystic Kidney Disease: A Qualitative Phenomenological Descriptive Study.
Nephron
January 2025
Department of Renal Medicine, Aarhus University Hospital, Aarhus, Denmark.
Introduction: Autosomal dominant polycystic kidney disease (ADPKD) is a prevalent hereditary kidney disease and the fourth most common cause of kidney failure. Patients may be aware of their condition from an early age or discover it unexpectedly, with varying levels of familial knowledge about the disease. This chronic condition presents significant challenges for healthcare professionals.
View Article and Find Full Text PDFAppetite-Control and Eating-Behavior Traits Might Not Be Impacted by a Single Weight-Cycling Episode in Weight-Cycling Athletes: Results of the Wave Study.
Int J Sports Physiol Perform
January 2025
Laboratory of the Metabolic Adaptations to Exercise Under Physiological and Pathological Conditions (AME2P) UPR 3533, CRNH Auvergne, Clermont Auvergne University, Clermont-Ferrand, France.
Purpose: The impact of weight cycling (WC)-successive weight loss (WL) and weight regain (WG)-on athlete performance is well documented, but effects on appetite are not. This study assessed the impact of a WC episode on dietary and appetitive profiles in athletes, considering sex and sport type.
Methods: Athletes (28 male, 20 female) from combat (n = 23), strength (n = 12), and endurance (n = 13) sports participated in 3 conditions during a WC episode (baseline, WL, WG).
Disentangling effects of the COVID-19 pandemic and Black Lives Matter protests on implicit anti-Black bias.
Acta Psychol (Amst)
January 2025
Kingsborough Community College, CUNY, United States.
Terror Management Theory (TMT) holds that mortal threats bolster people's desire to support their worldviews, which may contribute to increased outgroup bias. In 2020, two events likely increased mortality salience and death anxiety: COVID-19 and the Black Lives Matter (BLM) protests that followed George Floyd's murder. We used Project Implicit data to investigate their impact on implicit anti-Black bias, controlling for demographic variables.
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