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Landfill Leachate and Coagulants Addition Effects on Membrane Bioreactor Mixed Liquor: Filterability, Fouling, and Pollutant Removal.

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Article Synopsis
  • - The study evaluated the effectiveness of dynamic body-feed filtration (DBF) in removing bulky solids from equine hyperimmune plasma during snake antivenom production using caprylic acid, comparing various diatomites for optimal filtration performance.
  • - C1000 diatomite yielded the best results at 90 g/L concentration, demonstrating a recovery of immunoglobulins of 108 ± 4% in a scale-up to 50 L batches, while meeting quality specifications for the antivenoms.
  • - Unlike traditional open filtration systems, DBF offers enhanced microbiological safety due to its closed system design and faster filtration process, making it a cost-effective and compliant alternative for primary clarification in antivenom manufacturing.
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