AI Article Synopsis
- The text provides a historical overview of immunotoxicology, focusing on the early development of tests designed to predict harmful effects of chemicals on the immune system, such as immunosuppression and skin sensitization.
- It discusses how the field has evolved to enhance our understanding of basic science and improve assessments of risks to human health.
- Lastly, it emphasizes the need for more validated screening tests and highlights recent initiatives aimed at tackling gaps in various aspects of immunotoxicology, including allergies and autoimmune conditions.
Article Abstract
A brief historical perspective of immunotoxicology is presented describing the early development of predictive screening tests to identify xenobiotics that may cause immunosuppression or skin sensitization. This includes a discussion of the evolution of the discipline to support a better understanding of basic -science and improvement of human risk assessment. The last section describes the need for additional validated screening tests and recent efforts to address this gap in the other areas of immunotoxicology including food and respiratory allergy, autoimmunity and immunostimulation.
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| http://dx.doi.org/10.1007/978-1-60761-401-2_1 | DOI Listing |
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