Recently, information technology and microelectronics have enabled implanting miniature and highly intelligent devices within the brain for in-vitro diagnostic and therapeutic functions. Power and physical size constraints of these devices necessitate novel signal processing methods. In this paper we investigate an effective data acquisition and reconstruction method for brain implants based on Asynchronous Sigma Delta Modulators (ASDMs). The ASDMs are analog non-linear feedback systems capable of time coding signals. The proposed reconstruction algorithm is based on the Prolate Spheroidal Wave Function (PSWF) expansion of the sinc functions and the order of expansion is given by the input signal being coded. Multiplexing and transmission of the different channels of data are accomplished by chirp orthogonal frequency division multiplexing. Computer simulations using multi channel electroencephalographic data are performed for wireless transmission by brain implants for monitoring abnormal brain activities of epilepsy patients.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1109/IEMBS.2009.5333612 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
COMPARING DIRECTIONAL AND OMNIDIRECTIONAL DEEP BRAIN STIMULATION IN PARKINSON'S DISEASE PATIENTS.
Stereotact Funct Neurosurg
January 2025
Introduction: In 2015, directional leads have been released in Europe for deep brain stimulation (DBS) and have been particularly used for subthalamic nucleus (STN) DBS for Parkinson's disease (PD). In this study we aimed to compare an omnidirectional and directional leads cohort of PD patients when it comes to clinical effectiveness and to assess the correlation with volume of tissue activated - target overlap (VTA-target).
Methods: A total of 60 consecutive patients were retrospectively included.
Pitfalls and practical suggestions for using local field potential recordings in DBS clinical practice and research.
J Neural Eng
January 2025
Department of Neurology Neuroscience, University of Amsterdam, Meibergdreef 9, Amsterdam, 1105AZ, NETHERLANDS.
Local field potential (LFP) recordings using chronically implanted sensing-enabled stimulators are a powerful tool for indexing symptom presence and severity in neurological and neuropsychiatric disorders, and for enhancing our neurophysiological understanding of brain processes. LFPs have gained interest as input signals for closed-loop deep brain stimulation (DBS) and can be used to inform DBS parameter selection. LFP recordings using chronically implanted sensing-enabled stimulators have various implementational challenges.
View Article and Find Full Text PDFOptimal placement of high-channel visual prostheses in human retinotopic visual cortex.
J Neural Eng
January 2025
Faculty of Psychology, University of Maastricht, P.O. Box 616, 6200 MD Maastricht, The Netherlands, Maastricht, 6211 LK, NETHERLANDS.
Recent strides in neurotechnology show potential to restore vision in individuals afflicted with blindness due to early visual pathway damage. As neuroprostheses mature and become available to a larger population, manual placement and evaluation of electrode designs becomes costly and impractical. An automatic method to optimize the implantation process of electrode arrays at large-scale is currently lacking.
View Article and Find Full Text PDFNanoencapsulated Optical Fiber-Based PEC Microelectrode: Highly Sensitive and Specific Detection of NT-proBNP and Its Implantable Performance.
Anal Chem
January 2025
Hunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China.
Microelectrodes offer exceptional sensitivity, rapid response, and versatility, making them ideal for real-time detection and monitoring applications. Photoelectrochemical (PEC) sensors have shown great value in many fields due to their high sensitivity, fast response, and ease of operation. Nevertheless, conventional PEC sensing relies on cumbersome external light sources and bulky electrodes, hindering its miniaturization and implantation, thereby limiting its application in real-time disease monitoring.
View Article and Find Full Text PDFExtracellular Vesicles From Bone Marrow-Derived Macrophages Enriched in ARG1 Enhance Microglial Phagocytosis and Haematoma Clearance Following Intracerebral Haemorrhage.
J Extracell Vesicles
January 2025
Department of Neurosurgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Microglial phagocytosis of haematomas is crucial for neural functional recovery following intracerebral haemorrhage (ICH), a process regulated by various factors from within and outside the central nervous system (CNS). Extracellular vesicles (EVs), significant mediators of intercellular communication, have been demonstrated to play a pivotal role in the pathogenesis and progression of CNS diseases. However, the regulatory role of endogenous EVs on the phagocytic capacity of microglia post-ICH remains elusive.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!