This paper provides an introductory overview of recent microfabricated, as opposed to traditional chemically synthesized, magnetic resonance imaging (MRI) contrast agents. As a specific example of the enhanced agent functionality that top-down micro-engineering allows, the paper focuses on recently demonstrated magnetic microstructures that provide multispectral MRI contrast.
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http://dx.doi.org/10.1109/IEMBS.2009.5333677 | DOI Listing |
J Imaging
December 2024
Radiology Department, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
This study investigates radiomic efficacy in post-surgical traumatic spinal cord injury (SCI), overcoming MRI limitations from metal artifacts to enhance diagnosis, severity assessment, and lesion characterization or prognosis and therapy guidance. Traumatic spinal cord injury (SCI) causes severe neurological deficits. While MRI allows qualitative injury evaluation, standard imaging alone has limitations for precise SCI diagnosis, severity stratification, and pathology characterization, which are needed to guide prognosis and therapy.
View Article and Find Full Text PDFTalanta
April 2025
Department of Hepato-Pancreato-Biliary Surgery, The Affiliated Lihuili Hospital of Ningbo University, Ningbo, 315211, China; Health Science Center, Ningbo University, Ningbo, Zhejiang, 315211, China. Electronic address:
The hypoxic environment in tumors is closely linked to tumor structure, function, dissemination, invasion, metastasis, and drug resistance. Nitroreductase (NTR) is often recognized as a biomarker to evaluate the hypoxia degree for tumor cells. Traditional detection methods such as PET, MRI and multispectral photoacoustic tomography have limitations.
View Article and Find Full Text PDFNat Commun
September 2024
Department of Pediatrics and Adolescent Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, 91054, Germany.
Pompe disease (PD) is a rare autosomal recessive glycogen storage disorder that causes proximal muscle weakness and loss of respiratory function. While enzyme replacement therapy (ERT) is the only effective treatment, biomarkers for disease monitoring are scarce. Following ex vivo biomarker validation in phantom studies, we apply multispectral optoacoustic tomography (MSOT), a laser- and ultrasound-based non-invasive imaging approach, in a clinical trial (NCT05083806) to image the biceps muscles of 10 late-onset PD (LOPD) patients and 10 matched healthy controls.
View Article and Find Full Text PDFPlant Methods
September 2024
College of Information and Electrical Engineering, Shenyang Agricultural University, Shenyang, 110866, China.
Background: Wheat (Triticum aestivum L.) is an important grain crops in the world, and its growth and development in different stages is seriously affected by saline-alkali stress, especially in seedling stage. Therefore, nondestructive detection of wheat seedlings under saline-alkali stress can provide more comprehensive technical support for wheat breeding, cultivation and management.
View Article and Find Full Text PDFFood Chem
December 2024
Department of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, Xiamen University, Xiamen 361005, China. Electronic address:
Lycium barbarum L. (L. barbarum) is renowned worldwide for its nutritional and medicinal benefits.
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