AI Article Synopsis
- Multi-modality image-guided near infrared spectroscopy allows for the in-vivo measurement of total hemoglobin, oxygen saturation, water, and scatter in different body tissues.
- The accuracy of these measurements varies based on how far the imaging probe is from the tumor, with a 25% decrease in total hemoglobin accuracy for every centimeter from the tumor center.
- Effective image guidance and multi-plane acquisition techniques can enhance the precision of these measurements.
Article Abstract
Multi-modality image-guided near infrared spectroscopy provides volume-based quantification of total hemoglobin, oxygen saturation, water and scatter in various tissue types in-vivo. The accuracy of these parameters depends on the location of the imaging probe and its distance from the tumor. In a numerical study, we have performed simulation to analyze this effect in a breast-specific imaging domain. Results show that the accuracy of total hemoglobin decreases by 25% for every centimeter away from the tumor center, for a typical size of 35mm cancer in the breast. Image guidance is necessary for accurate positioning, and multi-plane acquisition can improve this accuracy.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860859 | PMC |
| http://dx.doi.org/10.1109/IEMBS.2009.5333426 | DOI Listing |
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