The all-cis hexose D-allose, fed to hamster fibroblast cultures over 14-20 hr, brings about a striking down-regulation of hexose transport. This down-regulation by allose is inhibited by 2,4-dinitrophenol. By using D-[14C]allose and thin-layer chromatography, two types of products accumulated that have been identified as allose and allose phosphate. We suspect that allose phosphate might be the down-regulator.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC51047 | PMC |
| http://dx.doi.org/10.1073/pnas.88.4.1504 | DOI Listing |
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