Patient history data are prominent in rheumatology patient management and should be captured at each visit as standard, quantitative, scientific data by a self-report questionnaire. Patient questionnaire data on a multidimensional health assessment questionnaire (MDHAQ) provide scores for physical function, pain, global estimate of status, and routine assessment of patient index data (RAPID3), which may be regarded as rheumatology vital signs. Patient questionnaires designed for usual clinical care, such as the MDHAQ, save time and improve the quality and documentation of the visit for the patient and the physician.
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Higher serotonin levels among patients with rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis compared to healthy controls assessed by liquid chromatography-tandem mass spectrometry (LC-MS).
Rheumatol Int
January 2025
Department of Rheumatology and Immunology, Jagiellonian University Medical College, Jakubowskiego 2, Kraków, 30-688, Poland.
Growing evidence suggests that serotonin is an important mediator in the cross-talk between immune and bone cells, playing a role in the pathogenesis of various types of inflammatory arthritis (IA). However, the relationship between circulating serotonin and different outcomes in three most prevalent IA - rheumatoid arthritis (RA), psoriatic arthritis (PsA), and axial spondyloarthritis (axSpA), remains limited and requires further investigation. This study was performed to evaluate variations in serotonin serum levels among RA, PsA, and axSpA and to explore the utility of this biochemical marker in the assessment of disease activity and health status measurements provided by the Multi-Dimensional Health Assessment Questionnaire (MDHAQ).
View Article and Find Full Text PDFCan a simple 0-10 RheuMetric physician estimate of inflammatory activity (DOCINF) depict a detailed swollen joint count (SJC) as accurately as a DAS28 or CDAI in patients with rheumatoid arthritis?
Semin Arthritis Rheum
October 2024
Department of Rheumatology, Liverpool Hospital, Sydney, Australia; South Western Sydney Rheumatology Research Group, Ingham Institute for Applied Medical Research; University of New South Wales, Medicine and Health, Kensington, Sydney, NSW 2052, Australia.
Objective: To compare a 0-10 physician subglobal estimate of inflammatory activity (DOCINF) on a RheuMetric checklist to a formal swollen joint count (SJC) and other rheumatoid arthritis (RA) Core data set measures in a disease activity score 28 (DAS28), clinical disease activity index (CDAI), and simplified disease activity index (SDAI) in patients with RA, recognizing that RA measures, index scores and physician global assessment (DOCGL) may be elevated by joint damage and patient distress, independent of inflamamtory activity, and that formal joint counts are not recorded at most routine care visits.
Methods: A cross-sectional study at a routine care visit included a RheuMetric checklist completed by a rheumatologist, with four 0-10 visual numeric scales (VNS) for DOCGL, and three sub-global estimates for inflammatory activity (DOCINF), joint damage (DOCDAM), and patient distress (DOCDIS), e.g.
Physician estimate of inflammation global assessment in explaining variations in swollen joint counts in rheumatoid arthritis patients.
Rheumatol Adv Pract
April 2024
Division of Rheumatology, Department of Medicine, Rush University School of Medicine, Chicago, IL, USA.
Objective: To analyse patients with RA for inflammatory activity by physician estimate of global assessment (DOCGL) an estimate of inflammatory activity (DOCINF) to explain variation in the swollen joint count (SJC).
Methods: Patients with RA were studied at routine care visits. Patients completed a multidimensional health assessment questionnaire (MDHAQ) and the physician completed a 28-joint count for swollen (SJC), tender (TJC) and deformed (DJC) joints and a RheuMetric checklist with a 0-10 DOCGL visual numeric scale (VNS) and 0-10 VNS estimates of inflammation (DOCINF), damage (DOCDAM) and patient distress (DOCSTR).
Ramosetron as an add-on therapy for refractory fibromyalgia: a randomized, double-blind, placebo-controlled trial.
Rheumatology (Oxford)
September 2024
Division of Rheumatology, Department of Internal Medicine, Chonnam National University Medical School & Hospital, Gwangju, Republic of Korea.
Objective: This study aimed to assess the efficacy and safety of intravenous ramosetron for pain relief in patients with fibromyalgia (FM) unresponsive to conventional treatments.
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Validation and Cultural Adaptation of Persian Version of Multidimensional Health Assessment Questionnaire in Rheumatoid Arthritis Patients.
Mediterr J Rheumatol
March 2024
Department of Community Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Background: Rheumatoid arthritis (RA) is a multidimensional disease. In addition to quantitative factors, qualitative factors play an important role in the progress and outcome of the diseases. One of the most effective methods of collecting qualitative information is questionnaires reported by patients.
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