GLUT4, a 12 transmembrane protein, plays a major role in insulin mediated glucose transport in muscle and adipocytes. For glucose transport, the GLUT4 protein needs to be translocated to the plasma membrane from the intracellular pool and it is possible that certain compounds may be able to enhance this process. In the present work, we have shown that gallic acid can increase GLUT4 translocation and glucose uptake activity in an Akt-independent but wortmannin-sensitive manner. Further analysis suggested the role of atypical protein kinase Czeta/lambda in gallic acid mediated GLUT4 translocation and glucose uptake.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.febslet.2009.11.092 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Bioactive Compounds and Fatty Acid Composition of Oils Obtained by Different Extraction Methods from Caper (Capparis ovata Desf.) Seeds.
J Oleo Sci
January 2025
Department of Plant Sciences, North Dakota State University.
In this study, the total phenol, total flavonoid content, antioxidant capacity, phenolic component and fatty acid profiles of caper seed oils extracted by solvent extraction, sonication extraction and cold press methods were revealed. Total phenol amounts of caper seed oils extracted by cold press, sonication and solvent systems were recorded as 0.10, 0.
View Article and Find Full Text PDFOil Composition and Phenolic Compounds of Plum Seeds Obtained from Fruit Processing By-products Treated by Heat.
J Oleo Sci
January 2025
Department of Plant Sciences, North Dakota State University.
In this study, the effect of microwave drying on oil content, bioactive compounds, antioxidant activity, polyphenols and fatty acid profiles of fresh (control) and dried plum kernels was investigated. The oil quantities of plum seeds dried were found between 27.40% (control) and 42.
View Article and Find Full Text PDFEffect of doping in TiO/chitosan composite on adsorptive-photocatalytic removal of gallic acid from water.
Chemosphere
January 2025
Department of Chemistry, School of Chemical Engineering and Physical Sciences, Lovely professional University, Phagwara, Punjab, India. Electronic address:
Gallic acid (GA) has emerged as a low biodegradable and high acidity industrial effluent. Due to mutagenic and carcinogenic nature of GA, it becomes essential to remove it from wastewater. Different chemical, physical and biological methods are being used for this purpose.
View Article and Find Full Text PDFAntioxidant, antidiabetic, and antimicrobial efficacy of germinated Ocimum gratissimum and Ocimum basilicum seed.
J Sci Food Agric
January 2025
University of Agricultural Sciences, Bengaluru, India.
Background: The edible seeds of Ocimum gratissimum and Ocimum basilicum were found to be a potent source of phytochemicals with noteworthy antioxidant, antidiabetic, and antimicrobial properties. This study aimed to investigate the impact of germination and extraction solvents (ethanol (EtOH), distilled water) on the therapeutic properties exhibited and the ability of seed extracts to act as natural food preservatives.
Results: The EtOH extracts of germinated O.
Supercritical fluid extraction and encapsulation of Rivas () flower: Principal component analysis (PCA).
Heliyon
January 2025
Department of Food Science and Engineering, Hamedan Branch, Islamic Azad University, Hamedan, Iran.
Supercritical CO modified by polar solvents can extract a wide variety of polar and non-polar chemical components compared to conventional methods. The current study aims to extract Rivas (Rheum ribes) flower using the ethanol modified supercritical CO (SCO-EOH) method; analyze its chemical compounds and bioactivity, encapsulate the extract in maltodextrin, gum-Arabic (GA), and their combination (GA + MD) using the spray drying method and investigate the differences among microparticles using Principal Component Analysis (PCA). The Rivas extract obtained by the SCO-EOH method was a rich source of unsaturated fatty acids (mainly linoleic acid: 57.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!