Resistance to oseltamivir was observed in influenza A pandemic (H1N1) 2009 virus isolated from an untreated person in Hong Kong, China. Investigations showed a resistant virus with the neuraminidase (NA) 274Y genotype in quasi-species from a nasopharyngeal aspirate. Monitoring for the naturally occurring NA 274Y mutation in this virus is necessary.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044550PMC
http://dx.doi.org/10.3201/eid1512.091057DOI Listing

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