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Endocrine disturbances in suprasellar germinomas.
Acta Endocrinol (Copenh)
March 1989
Department of Neurosurgery, University of Erlangen-Nürnberg, FRG.
The authors have investigated hypothalamic-pituitary function in 8 patients (aged 9-27 years) with surgically and histologically proven suprasellar germinomas. Diabetes insipidus was found in 7 patients. All the patients had hypogonadism and hypocortisolism as judged by dynamic endocrine testing.
View Article and Find Full Text PDF[Hyperprolactinemic hypogonadism--pathogenesis, diagnosis and therapy].
Z Gesamte Inn Med
October 1979
About 30% of amenorrhoeic women have a disturbed prolactin secretion. In about 10% the cause is a hypophyseal-suprahypophyseal tumour. Taking into consideration the degree of severity of the galactorrhoe, the amenorrhoe is connected with incontinence of milk.
View Article and Find Full Text PDFProlonged coma afterhead trauma is associated with depletion of 3', 5' cyclic adenosine monophosphate (cAMP) in the cerebrospinal fluid (CSF). Because cAMP has previously been implicated in neurorendocrine secretion, this study examines the pituitay-hypothalamic function in 15 adult male patients (to exclude the effects of puberty and menses) with traumatic coma lasting longer than 2 weeks. Ventricular CSF cAMP was measured at 2- to 4-day intervals for 10 to 25 days.
View Article and Find Full Text PDFSuprahypophyseal dysfunction in a patient with asexual ateleiosis.
Acta Endocrinol (Copenh)
March 1978
The neuroendocrine function of a 19 years old female dwarf with primary amenorrhoea and lack of sexual development (asexual ateleiosis) was studied. Undetectable fasting plasma levels of growth hormone (GH) and a lack of response to three different provocative stimuli was observed. Oestrogen administratin did not modify the GH response.
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