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| http://dx.doi.org/10.5688/aj7307124 | DOI Listing |
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Sex-associated differences in incentive salience and drinking behaviour in a rodent model of alcohol relapse.
Addict Biol
January 2025
Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, Berlin, Germany.
The ability of environmental cues to trigger alcohol-seeking behaviours is thought to facilitate problematic alcohol use. Individuals' tendency to attribute incentive salience to cues may increase the risk of addiction. We sought to study the relationship between incentive salience and alcohol addiction using non-preferring rats to model the heterogeneity of human alcohol consumption, investigating both males and females.
View Article and Find Full Text PDFElectronic cigarette usage amongst high school students in South Africa: a mixed methods approach.
EClinicalMedicine
December 2024
Utrecht University, Department of Interdisciplinary Social Science, Netherlands.
Background: The WHO has highlighted that: "promotion of e-cigarettes has led to marked increases in e-cigarette use by children and adolescents." The long-term neuropsychiatric and psychological consequences of substance abuse in adolescence is well recognised. Limited data exists on the adolescent burden of vaping-related nicotine addiction and behavioural and/or psychological dependence to guide pharmacological or behavioural interventions to stop electronic cigarette usage.
View Article and Find Full Text PDFChronic nicotine exposure induces molecular and transcriptomic endophenotypes associated with mood and anxiety disorders in a cerebral organoid neurodevelopmental model.
Front Pharmacol
December 2024
Addiction Research Group, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada.
Introduction: Prenatal nicotine exposure (PNE) from maternal smoking disrupts regulatory processes vital to fetal development. These changes result in long-term behavioral impairments, including mood and anxiety disorders, that manifest later in life. However, the relationship underlying PNE, and the underpinnings of mood and anxiety molecular and transcriptomic phenotypes remains elusive.
View Article and Find Full Text PDFPromoting safer gambling through social norms and goal setting: A qualitative process analysis of participants' experiences in the EROGamb 2.0 feasibility trial.
Internet Interv
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Bournemouth University, Poole, United Kingdom.
Gambling, though a popular social activity, can lead to addiction and cause significant harm. This study aimed to explore the experiences of 36 low-to-moderate risk gamblers (PGSI score 0-7; 31 male, 5 female; 10 per each intervention arm, 6 per control group) in the 'EROGamb 2.0' feasibility trial ( = 168).
View Article and Find Full Text PDFAs of 2023, 69% of adults and 81% of teens in the U.S. use social media.
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