Objective: To estimate the sensitivity and specificity of dynamic helical CT scanning for detecting pelvic lymph node metastasis in patients with uterine cervix carcinoma.
Methods: Totally 275 patients with pathologically confirmed uterine cervix carcinoma from Jun 2005 to Jul 2007 included bilateral pelvic lymphadenectomy were eligible. CT was performed within 30 days of surgery. The imaging and pathologic findings for each patient and each side pelvic lymph node were compared.
Results: The finding of pathology as reference standard, according to diagnostic criteria of most diameter > or = 10 mm or > or = 15 mm with or without central necrosis of imaging of each side pelvic lymph node as the positive diagnosis of CT scan, respectively. The sensitivity and specificity of CT in predicting nodal metastasis were determined. The sensitivity was 62.0%, 33.8%, respectively, and the specificity was 93.5%, 99.0%, respectively.
Conclusions: Dynamic helical CT is moderately specific in predicting lymph node metastasis pre-operatively in patients with uterine cervix carcinoma. The sensitivity is rather higher according to diagnostic criteria of most diameter > or = 10 mm.
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