Femur metastasis in carcinoma of the uterine cervix: a rare entity.

Arch Gynecol Obstet

Gynecologic Oncology Unit, Department of Oncology, Catholic University of the Sacred Heart, L.go A. Gemelli, 1, 86100, Campobasso, Italy.

Published: May 2010

Purpose: We report the first case of isolated femur metastasis in a locally advanced cervical cancer (LACC) patients.

Case: A 40-year-old woman presenting with carcinoma of the uterine cervix, FIGO stage IIb was administered concomitant chemo-radiation and achieved clinical partial response. Before the planned surgery, she developed an isolated metastatic lytic lesion of the left femur. After surgical excision of metastasis, she refused palliative chemotherapy, and radiotherapy, and died 3 months later because of progression of the disease.

Conclusion: Bone metastasis is not so infrequent in patients with LACC. Because the prognosis of these patients is poor and most of them die within 1 year after the diagnosis of metastatic disease, the policy of treatment should be directed to maintain their quality of life.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848922PMC
http://dx.doi.org/10.1007/s00404-009-1307-6DOI Listing

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