To assess the usefulness of a new rapid chromatographic immunoassay test for the detection of adenovirus, a prospective 3-year study was conducted in 587 febrile outpatient children suspected of adenovirus infection. A total of 332 children were diagnosed with this infection, using a viral culture. The sensitivity and specificity of the rapid test were 89.2% and 98.0%, respectively.

Download full-text PDF

Source
http://dx.doi.org/10.1097/INF.0b013e3181bd5059DOI Listing

Publication Analysis

Top Keywords

chromatographic immunoassay
8
immunoassay test
8
rapid diagnosis
4
diagnosis adenovirus
4
adenovirus respiratory
4
respiratory tract
4
tract infections
4
infections chromatographic
4
test pediatric
4
pediatric outpatient
4

Similar Publications

: Testosterone is an androgenic hormone that plays important roles in both males and females. The circulating levels of total testosterone vary from 1 to 1480 ng/dL. High-throughput immunoassays often lack accuracy in lower concentration ranges (below 100 ng/dL), particularly when used for females or children.

View Article and Find Full Text PDF

A Sensitive Radioimmunoassay for T3 and T4 Determinations in Plasma and Tissues.

Methods Mol Biol

November 2024

Laboratory of Thyroid Hormones and Central Nervous System, Department of Neurological Diseases and Aging, Instituto de Investigaciones Biomédicas Sols-Morreale, Consejo Superior de Investigaciones Científicas (CSIC), Universidad Autónoma de Madrid (UAM), Madrid, Spain.

This chapter details protocols for determining plasma thyroid hormone (TH) levels and tissue TH content by competitive radioimmunoassays (RIAs). These protocols include: an initial test of the chromatographic performance, isotopic labeling to produce high activity I-T3 and I-T4, free iodide estimation of the labeled products, purification of tracers from iodide by paper electrophoresis, extraction of THs from plasma and tissue samples, and the RIA procedures. The RIA involves the competition between radioactive labeled and unlabeled hormones for specific antibody binding, and due to its high sensitivity is capable of detecting a minimum of 2.

View Article and Find Full Text PDF

A comprehensive review on the pretreatment and detection methods of nitrofurans and their metabolites in animal-derived food and environmental samples.

Food Chem X

December 2024

Chongqing Key Laboratory of Conservation and Utilization of Freshwater Fishes, Animal Biology Key Laboratory of Chongqing Education Commission of China, College of Life Sciences, Chongqing Normal University, Chongqing 401331, China.

In recent years, the residues of nitrofurans (NFs) and their metabolites in animal-derived food and environmental samples have gained widespread attention. The parent drugs and their metabolites have displayed significant toxicity to human health including carcinogenic, mutagenic and teratogenic effects, leading to banned in animal husbandry in many countries. Hence, monitoring the residues of NFs is necessary to guarantee public health and ecological security.

View Article and Find Full Text PDF

Development and Diagnosis Performance of IgM-Based Rapid Antigen Test for Early Detection of SARS-CoV-2 Infection in a Large Cohort of Suspected COVID-19 Cases - USA, Poland, and Sweden, 2021-2022.

China CDC Wkly

September 2024

Key Laboratory of Biomarkers and In Vitro Diagnosis Translation of Zhejiang province, School of Laboratory Medicine and Bioengineering, Hangzhou Medical College, Hangzhou City, Zhejiang Province, China.

Article Synopsis
  • - Antigen testing is vital for managing the COVID-19 pandemic, and this study compared a new IgM-based rapid antigen test to the standard RT-PCR method for detecting SARS-CoV-2.
  • - The study analyzed 1,030 nasopharyngeal swab samples and found that the antigen test showed very high sensitivity (93.18%-100%) and specificity (99.67%-100%) across different testing centers, with performance improving under certain conditions.
  • - The ALLtest Ag-RDT proved to be a reliable tool for diagnosing COVID-19, suggesting it could be an effective option for early detection in suspected cases.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!