Two stereoisomers of cyclobutane derivatives with pyridyl and carboxylic acid functionalities have been stereoselectively synthesized by a solid-state photochemical [2 + 2] cycloaddition reaction in quantitative yields. The head-to-head and head-to-tail parallel orientations of the monomers, required to obtain these two isomers, have been controlled by the anions present in the salts. The photoinert behavior of these salts in solution signifies the importance of the solid-state synthesis of these cyclobutane derivatives.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/ol9025233 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Luminescent cyclometalated gold(iii) complexes covalently linked to metal-organic frameworks for heterogeneous photocatalysis.
Chem Sci
December 2024
Department of Chemistry, State Key Laboratory of Synthetic Chemistry, The University of Hong Kong Pokfulam Road Hong Kong P. R. China
Phosphorescent gold(iii) complexes possess long-lived emissive excited states, making them ideal for use as molecular sensors and photosensitizers for organic transformations. Literature reports indicate that gold(iii) emitters exhibit good catalytic activity in homogeneous photochemical reactions. Heterogeneous metal-organic framework (MOF)-supported gold(iii) photocatalysts are considered to show high recyclability in photochemical reactions and potentially provide new selectivities.
View Article and Find Full Text PDFChemical composition and insecticidal activity of Mentha rotundifolia and Chrysanthemum coronarium essential oils against the tomato leaf miner, Tuta absoluta.
Sci Rep
January 2025
Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box.2455, Riyadh, 11451, Saudi Arabia.
Tuta absoluta is one of the most destructive pests of tomatoes. Chemical insecticides used to control this leafminer harm all organisms, increasing the risk to public health and the environment. Developing natural alternatives, such as bioinsecticides formulated from essential plant oils, is a key strategy to address this problem.
View Article and Find Full Text PDFAsymmetric synthesis of atropisomers featuring cyclobutane boronic esters facilitated by ring-strained B-ate complexes.
Nat Commun
December 2024
School of Physical Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
The strain-release-driven reactions of bicyclo[1.1.0]butanes (BCBs) have received significant attention from chemists.
View Article and Find Full Text PDFHafnium-Based Metal-Organic Framework Nanosystems Entrapping Squaraines for Efficient NIR-Responsive Photodynamic Therapy.
ACS Appl Mater Interfaces
January 2025
Department of Chemistry, NIS Interdepartmental and INSTM Reference Centre, University of Torino, Via G. Quarello 15/A, 10135 and Via P. Giuria 7, 10125 Turin, Italy.
In this study, we present for the first time the incorporation of two distinct nonsymmetrical squaraines (SQ) into hierarchically porous Hafnium-based UiO-66 Metal-Organic Frameworks (MOFs), each functionalized with various moieties, for application as photosensitizers in photodynamic therapy. SQs are meticulously designed to feature COOH moieties for interaction with the MOF's metallic cluster and bromine atoms to enhance intersystem crossing and reactive oxygen species (ROS) production. The distinct central functionalizations, one with squaric acid and the other with a dicyanovinyl-substituted squaric acid derivative, result in unique geometric conformations.
View Article and Find Full Text PDFIsolation and Biomimetic Semisynthesis of Hyperzrones A and B, Two Nor-Polycyclic Polyprenylated Acylphloroglucinols with a Characteristic Cyclobutane Moiety, from .
Org Lett
December 2024
Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, People's Republic of China.
Article Synopsis
- Two new compounds, Hyperzrones A and B, are unique polycyclic polyprenylated acylphloroglucinols with a cyclobutane structure.
- Their structures were confirmed using a combination of spectroscopic analysis, X-ray crystallography, and quantum chemical calculations.
- A bioinspired method was developed to synthesize these compounds from hypercalin B, along with creating various derivatives for further biological research.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!