Population data of 17 Y-STR loci from Rio Grande do Sul state (South Brazil).

Forensic Sci Int Genet

Setor de Genética Forense, Laboratório de Perícias, Instituto-Geral de Perícias, Secretaria da Segurança Pública do Estado do Rio Grande do Sul, Porto Alegre, RS, Brazil.

Published: December 2009

AI Article Synopsis

  • A study examined the Y-STR loci of 255 Brazilian males from Rio Grande do Sul, identifying 247 haplotypes, with 239 being unique.
  • The haplotype diversity was 99.98% and the discrimination capacity was 96.86%.
  • The RS population's genetic distance showed similar traits to certain areas in Brazil and Argentina, while differing significantly from regions like Spain and Germany.

Article Abstract

A sample of 255 Brazilian males from Rio Grande do Sul (RS), the Brazilian southernmost state, was typed for 17 Y-STR loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635, YGATA_H4.1 and DYS385ab). A total of 247 haplotypes were identified, of which 239 were unique and eight were found in two individuals each. The haplotype diversity (99.98%) and discrimination capacity (96.86%) were calculated. Pairwise haplotype distances showed that the RS population is not significantly different from Brazil, Rio de Janeiro, and Argentina, is different from São Paulo, Italy, and North Portugal, and is very distant from Spain, the Amazon region, Germany, and South Amerindians. When the RS data was separated in the seven geopolitical regions, some pairs of regions were significantly different; however no region was different from the whole Brazilian sample.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fsigen.2009.02.001DOI Listing

Publication Analysis

Top Keywords

y-str loci
8
rio grande
8
grande sul
8
population data
4
data y-str
4
loci rio
4
sul state
4
state south
4
south brazil
4
brazil sample
4

Similar Publications

Autosomal and Y-STR genetic database from a population of the Spanish Civil War (1936-1939) and the postwar period.

Int J Legal Med

January 2025

Laboratory of Forensic and Population Genetics, Legal Medicine, Psychiatry and Pathology Department, Medicine School, Complutense University of Madrid, Madrid, 28040, Spain.

Under the initiative of the "Direcció General de Memòria democràtica-Departament de Justícia" (Generalitat of Catalonia, Spain), a multi-disciplinar project was funded to identify the remains of people disappeared in Catalonia during and after the Spanish Civil War (1936-1939). Samples were officially sent by Autonomous Government of Catalonia to the Laboratory of Forensic and Population Genetics at Complutense University, Madrid, Spain, to be genotyped. Our study presents a database of 343 victims genotyped for STRs comprised in GlobalFiler™ PCR Amplification Kit (Thermofisher Scientific) and a subset of 292 typed with Y-STRs from Yfiler™ Plus PCR Amplification Kit (Thermofisher Scientific).

View Article and Find Full Text PDF

Evaluating genome-wide and targeted forensic sequencing approaches to kinship determination.

Forensic Sci Int Genet

January 2025

Department of Genetics, Genomics & Cancer Sciences, University of Leicester, University Road, Leicester, UK. Electronic address:

Kinship determination is a valuable tool in forensic genetics, with applications including familial searching, disaster victim identification, and investigative genetic genealogy. Conventional typing of small numbers of autosomal short tandem repeats (STRs) confidently identifies only first-degree relatives. Massively parallel sequencing (MPS) can access more STRs and resolve alleles identical by length but differing in sequence (isoalleles), which may increase the power of kinship estimation, particularly when combined with additional sequenced single nucleotide polymorphism (SNP) loci, as in the ForenSeq DNA Signature Prep kit.

View Article and Find Full Text PDF

Evaluation of RMplex system for differentiating father-son pairs using Y-STRs in a Korean population.

Forensic Sci Int Genet

January 2025

Forensic DNA Division, National Forensic Service, Wonju, South Korea. Electronic address:

Y-chromosomal short tandem repeats (Y-STRs) at rapidly mutating (RM) loci have been suggested as tools for differentiating paternally related males. RMplex is a recently developed system that incorporates 26 RM loci and four fast-mutating (FM) loci, targeting 44 male-specific loci. Here, we evaluated the RMplex by estimating Y-STR mutation rates and the overall differentiation rates for 542 Korean father-son pairs, as well as the genetic population values for 409 unrelated males.

View Article and Find Full Text PDF

This study investigates the Y-chromosome genetic diversity of the Turkmen population in Turkmenistan, analyzing 23 Y-STR loci for the first time in a sample of 100 individuals. Combined with comparative data from Turkmen populations in Afghanistan, Iran, Iraq, Russia, and Uzbekistan, this analysis offers insights into the genetic structure and relationships among Turkmen populations across regions across Central Asia and the Near East. High haplotype diversity in the Turkmen of Turkmenistan is shaped by founder effects (lineage expansions) from distinct haplogroups, with haplogroups Q and R1a predominating.

View Article and Find Full Text PDF

Y-chromosome short tandem repeats (Y-STRs) loci have significant research and application value in individual identification, parentage testing, kinship determination and genealogical DNA analysis due to their unique genetic characteristics. Currently, various commercial STR typing kits have used in forensic detection, which greatly promoting the scientific application of STR in criminal investigation and judicial trials. However, due to the complexity and specificity of biological samples, the special STR typing in the sample poses certain difficulties for the construction of DNA databases.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!